Connective Tissues

Biochemistry and Pathophysiology

  • Reinhard Fricke
  • Fritz Hartmann

Table of contents

  1. Front Matter
    Pages I-XII
  2. Structure

  3. Synthesis

  4. Degradation

    1. Front Matter
      Pages 129-129
    2. E. Buddecke, H. Kresse
      Pages 131-145
    3. R. I. G. Morrison
      Pages 150-157
    4. C. H. Pearson, F. Happey, A. Naylor, J. M. Osborn, R. L. Turner
      Pages 158-165
    5. H. Greiling, R. Kisters, H. W. Stuhlsatz, A. Eberhard
      Pages 166-172
    6. J. M. Evanson
      Pages 173-176
    7. J. Lindner, K. Grasedyck, G. Prinz, J. Grade, H. Kölln
      Pages 180-190
  5. Immunobiology

    1. Front Matter
      Pages 199-199
    2. G. Uhlenbruck, A. Rothe, O. Prokop
      Pages 201-220
  6. Pathophysiology

  7. Back Matter
    Pages 305-309

About this book


connective tissues are essential for the physical functioning of the animals's body. The condition of the various connective tissues is governed by biochemical factors, anabolism and catabolism, that are controlled by specific enzymes. Any change outside the normal range of metabolism, for instance induced by immunological reactions, may induce a pathological disturbance. The result can be acute or chronic inflammation, or loss of normal function, expressed in loosening, dilatation, breaking, wear, stiffness, shrinking, scars, stenosis, and cirrhosis or any other kind of fibrosis. A first step toward improving our understanding of the feedback mecha­ nism that maintains the biological status and texture of a given connective tissue is to combine what is known about synthesis and enzymatic degradation of the components of fibers and ground substance. Common pathological phenomena like chronic inflammation of immune reactions can be either the result of the cause of disturbances in the sensitive balance of connective tissue metabolism. Nowadays con­ nective tissues are less and less regarded as brady trophic tissue but rather as a stimulating and many-sided problem of research. Before we can understand the pathogenesis of the connective tissue diseases that result in the destructive processes mentioned above, basic research will be necessary. This research will be furthered by a constant exchange of information and the results of· observations. To promote this exchange of information between scientists, symposia on connective tissue research are organized at regular intervals.


Tissues biochemistry chemistry diseases inflammation metabolism physiology tissue

Editors and affiliations

  • Reinhard Fricke
    • 1
  • Fritz Hartmann
    • 1
  1. 1.Medizinische PoliklinikHannover-KleefeldGermany

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 1974
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-642-61934-2
  • Online ISBN 978-3-642-61932-8
  • Buy this book on publisher's site