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Transgenic Organisms and Biosafety

Horizontal Gene Transfer, Stability of DNA, and Expression of Transgenes

  • Erwin R. Schmidt
  • Thomas Hankeln

Table of contents

  1. Front Matter
    Pages I-XX
  2. Horizontal Gene Transfer

    1. Front Matter
      Pages 1-1
    2. P. Capy, C. Bazin, D. Anxolabéhère, T. Langin
      Pages 15-30
    3. J. Landsmann, E. Graser, A. Riedel-Preuß, C. van der Hoeven
      Pages 71-76
    4. P. J. Dale, J. A. Scheffler
      Pages 85-93
    5. D. Mitten, K. Redenbaugh, J. Lindemann
      Pages 95-100
    6. D. Klehr-Wirth, M. Wirth, R. Grannemann, C. Münk, H. Häuser
      Pages 105-115
    7. W. Doerfler, K. Fechteler, H. Heller, C. Kämmer, M. Knoblauch, P. Koetsier et al.
      Pages 125-133
  3. Stability of DNA

  4. Expression of Transgenes

    1. Front Matter
      Pages 209-209
    2. J. Landsmann, C. van der Hoeven, A. Dietz-Pfeilstetter
      Pages 223-230
    3. A. Dietz-Pfeilstetter, V. Kay, J. Landsmann, J. Bode
      Pages 261-268
    4. M. Fladung, M. R. Ahuja
      Pages 275-281
  5. Field Release of Transgenic Plants

    1. Front Matter
      Pages 303-303
    2. D. Bartsch, A. Emonds, H. Gluth, C. Haag, C. Morak, M. Pohl-Orf et al.
      Pages 319-329
  6. Back Matter
    Pages 331-335

About these proceedings

Introduction

In the fast developing field of gene and biotechnology the construction and use of transgenic organisms play an increasingly important role. A frequently asked question is whether these genetically modified organisms are safe if used either in laboratory containments or in the open field. This holds especiall true for the commercialization of transgenic organisms. An important aspect of "Biosafety" is the stability of transgenic DNA and the reliable expression of the transgene. A second aspect is the potential for horizontal gene transfer from transgenic to non-transgenic organisms. Most of the articles deal with these important questions. The book may thus contribute to the public debate about the biosafety of transgenic organisms by presenting original experimental data as well as theoretical considerations. Some of the contributions are useful reviews of the relevant literature. The book does not only contain academic research articles, a number of the reports are written by "practitioners" actually using gene technology in the pharmaceutical and agro-industries. Thus, the interested reader can find a broad range of information on purely academic questions as well as on problems which gene technology companies have to cope with when a transgenic organism is to be field-tested and commercialized.

Keywords

Activation Biosafety DNA DNA-stability Transgene Expression Transgenic Organisms gene transfer genes

Editors and affiliations

  • Erwin R. Schmidt
    • 1
  • Thomas Hankeln
    • 1
  1. 1.Institut für Molekulargenetik, Gentechnologische Sicherheitsforschung und BeratungJohannes Gutenberg-Universität MainzMainzGermany

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-642-61460-6
  • Copyright Information Springer-Verlag Berlin Heidelberg 1996
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-540-61077-9
  • Online ISBN 978-3-642-61460-6
  • Buy this book on publisher's site