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Clinical Epidemiology and Biostatistics

A Primer for Clinical Investigators and Decision-Makers

  • Michael S. Kramer

Table of contents

  1. Front Matter
    Pages I-XII
  2. Epidemiologic Research Design

    1. Front Matter
      Pages 1-1
    2. Michael S. Kramer
      Pages 3-10
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      Pages 11-24
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      Pages 25-36
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      Pages 37-46
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      Pages 47-57
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      Pages 58-77
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      Pages 78-92
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      Pages 93-112
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      Pages 113-117
  3. Biostatistics

    1. Front Matter
      Pages 119-119
    2. Michael S. Kramer
      Pages 121-123
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      Pages 124-136
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      Pages 137-145
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      Pages 146-164
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      Pages 165-186
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      Pages 187-198
  4. Special Topics

    1. Front Matter
      Pages 199-199
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      Pages 201-219
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      Pages 220-235
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      Pages 236-253
    5. Michael S. Kramer
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  5. Back Matter
    Pages 271-286

About this book

Introduction

Here is a book for clinicians, clinical investigators, trainees, and graduates who wish to develop their proficiency in the planning, execution, and interpretation of clinical and epidemiological research. Emphasis is placed on the design and analysis of research studies involving human subjects where the primary interest concerns principles of analytic (cause-and- effect) inference. The topic is presented from the standpoint of the clinician and assumes no previous knowledge of epidemiology, research design or statistics. Extensive use is made of illustrative examples from a variety of clinical specialties and subspecialties. The book is divided into three parts. Part I deals with epidemiological research design and analytic inference, including such issues as measurement, rates, analytic bias, and the main forms of observational and experimental epidemiological studies. Part II presents the principles and applications of biostatistics, with emphasis on statistical inference. Part III comprises four chapters covering such topics as diagnostic tests, decision analysis, survival (life-table) analysis, and causality.

Keywords

biostatistics clinical epidemiology correlation descriptive statistics epidemiologic research epidemiological epidemiology

Authors and affiliations

  • Michael S. Kramer
    • 1
  1. 1.Faculty of MedicineMcGill UniversityMontrealCanada

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-642-61372-2
  • Copyright Information Springer-Verlag Berlin Heidelberg 1988
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-642-64814-4
  • Online ISBN 978-3-642-61372-2
  • Buy this book on publisher's site