The Projections to the Spinal Cord of the Rat During Development: A Timetable of Descent

  • E. A. J. F. Lakke

Part of the Advances in Anatomy Embryology and Cell Biology book series (ADVSANAT, volume 135)

Table of contents

  1. Front Matter
    Pages I-XIV
  2. E. A. J. F. Lakke
    Pages 1-5
  3. E. A. J. F. Lakke
    Pages 7-11
  4. E. A. J. F. Lakke
    Pages 43-50
  5. E. A. J. F. Lakke
    Pages 99-115
  6. E. A. J. F. Lakke
    Pages 117-118
  7. Back Matter
    Pages 119-143

About this book


The studies described here were carried out in the Neuroregulation Group at the Department of Physiology of the University of Leiden. Over the last decade this group has, in close collaboration with the departments of neurosurgery and urology of the Academic Hospital of Leiden, studied development and regeneration of the spinal cord and its peripheral nerves both from a neuroanatomical and a clinical perspective. During this period the development of brainstem projections to the spinal cord of the rat was studied with a retrograde tracing technique. Horseradish peroxidase was injected into the spinal cord of rat fetuses, both at different ages, and at different levels of the spinal cord. These studies aimed to discover regularities in the behavior of descending fiber systems that could yield insight into the logic that the nervous system must employ to structure its connectional pattern during development. Such insight might then be applied to improve regeneration of the nervous system.


development enzyme neurophysiology physiology somatotopy spinal cord

Authors and affiliations

  • E. A. J. F. Lakke
    • 1
  1. 1.Department of Physiology Neuroregulation GroupUniversity of LeidenLeidenThe Netherlands

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 1997
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-540-61878-2
  • Online ISBN 978-3-642-60601-4
  • Series Print ISSN 0301-5556
  • Series Online ISSN 2192-7065
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