About these proceedings
The quality of animal models used in biomedical research has increased substantially since the first successful microinjections of foreign DNA fragments into a mouse zygote in the early 1980s. New well-defined animal models developed either by microinjection techniques or by homologous recombination in embryonic stem (ES) cells, have become widely available and several classical animal models have now been replaced by these transgenic models. Transgenic animals also fulfill increasingly important roles in other fields, like livestock production or in biopharming. In the framework of the European Commission's Biotechnology Programme, a workshop has been organized at Utrecht University (30 October, 1995) with leading experts in the field of animal transgenesis and animal welfare as presenting authors. This book summarizes the papers presented at the workshop.
animal model ethics mutation research transgenesis transgenic techniques veterinary science