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Risk and Progression Factors in Carcinogenesis

  • H. K. Müller-Hermelink
  • H.-G. Neumann
  • W. Dekant

Part of the Recent Results in Cancer Research book series (RECENTCANCER, volume 143)

Table of contents

  1. Front Matter
    Pages I-XII
  2. Interaction of Carcinogens with Cellular DNA

    1. D. Burnouf, M. Bichara, C. Dhalluin, A. Garcia, R. Janel-Bintz, N. Koffel-Schwartz et al.
      Pages 1-20
    2. W. Adam, S. Andler, D. Ballmaier, S. Emmert, B. Epe, G. Grimm et al.
      Pages 21-34
    3. D. Ballmaier, M. Pflaum, C. Kielbassa, B. Epe
      Pages 35-47
    4. L. H. F. Mullenders, A. van Hoffen, M. P. G. Vreeswijk, H.-J. Ruven, H. Vrieling, A. A. van Zeeland
      Pages 89-99
  3. Analysis of Cellular Alterations and Growth Dysregulation in Cancer Cells

    1. P. J. Wirth, L.-di Luo, T. Hoang, T. Benjamin
      Pages 145-160
    2. A. Bitsch, J. Fecher, M. Jost, P.-C. Klöhn, H.-G. Neumann
      Pages 209-223
    3. U. Naumann, I. Eisenmann-Tappe, U. R. Rapp
      Pages 237-244
    4. J. Troppmair, U. R. Rapp
      Pages 245-249
    5. T. Schuster, C. Price, W. Rossoll, B. Kovacech
      Pages 251-261
    6. E. Christenson, A. J. DeMaggio, M. F. Hoekstra
      Pages 263-274
  4. Selected Findings in Human Tumors

    1. R. C. Grafström, U. G. Norén, X. Zheng, Å. Elfwing, K. Sundqvist
      Pages 275-306
    2. G. Ott, M. M. Ott, J. Kalla, A. Helbing, B. Schryen, T. Katzenberger et al.
      Pages 307-319
    3. F. Gieseler, A. Glasmacher, D. Kämpfe, C. Zernak, S. Valsamas, J. Kunze et al.
      Pages 321-327
    4. W. Liebetrau, T. M. Rünger, A. Baumer, C. Henning, O. Gross, D. Schindler et al.
      Pages 353-367
    5. M. Hollstein, T. Soussi, G. Thomas, M.-C. von Brevern, H. Bartsch
      Pages 369-389
  5. Back Matter
    Pages 391-395

About these proceedings

Introduction

The principal goal of experimental carcinogenesis is the elucidation of mechanisms and factors that might be of relevance for the formation of human tumors. Specialization, as necessary as it may be, however, may prevent the transfer of knowledge among disciplines involved in cancer research. Leading scientists give insight into mechanisms of carcinogen-induced DNA damage and mutagenicity, and cellular responses including DNA repair, cellular stress, apoptosis, and regulation of cellular growth. Selected human tumor models of oral epithelium, skin cancer, and malignant lymphoma are analyzed in order to determine the most relevant primary genetic alteration in cell-specific transformation. Finally, the epidemiology of p53 mutation is considered as an indication of specific pathogenetic factors in sporadic human tumors.

Keywords

DNA DNA-repair Experimentelle Karzingogenese Humantumore UV-induced carcinogenesis UV-induzierte Karzinogenese apoptosis cancer carcinogenesis cell human tumors leukemia lymphoma mutagen skin cancer

Editors and affiliations

  • H. K. Müller-Hermelink
    • 1
  • H.-G. Neumann
    • 2
  • W. Dekant
    • 2
  1. 1.Pathologisches Institutder Universität WürzburgWürzburgGermany
  2. 2.Institut für Pharmakologie und Toxikologieder Universität WürzburgWürzburgGermany

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-642-60393-8
  • Copyright Information Springer-Verlag Berlin Heidelberg 1997
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-642-64385-9
  • Online ISBN 978-3-642-60393-8
  • Series Print ISSN 0080-0015
  • Buy this book on publisher's site