Mechanisms of B Cell Neoplasia 1998

Proceedings of the Workshop held at the Basel Institute for Immunology 4th–6th October 1998

  • Fritz Melchers
  • Michael Potter
Conference proceedings

Part of the Current Topics in Microbiology and Immunology book series (CT MICROBIOLOGY, volume 246)

Table of contents

  1. Front Matter
    Pages I-XXIX
  2. B Cell and Plasma Cell Development

    1. Front Matter
      Pages 1-1
    2. E. ten Boekel, T. Yamagami, J. Andersson, A. G. Rolink, F. Melchers
      Pages 3-10
    3. R. Ceredig, A. G. Rolink, F. Melchers, J. Andersson
      Pages 11-19
    4. T. E. I. Taher, R. van der Voort, L. Smit, R. M. J. Keehnen, E. J. M. Schilder-Tol, M. Spaargaren et al.
      Pages 31-38
    5. A. G. Rolink, F. Melchers, J. Andersson
      Pages 39-44
    6. K. Yang, M. Davila, G. Kelsoe
      Pages 53-62
    7. R. A. Manz, G. Cassese, A. Thiel, A. Radbruch
      Pages 71-75
  3. Chemokines and Chemokine Receptors

    1. Front Matter
      Pages 77-77
    2. V. Pevzner, I. Wolf, R. Burgstahler, R. Förster, M. Lipp
      Pages 79-85
    3. J. G. Cyster, V. N. Ngo, E. H. Ekland, M. D. Gunn, J. D. Sedgwick, K. M. Ansel
      Pages 87-93
    4. C. S. Rabkin, S. Sei
      Pages 111-115
    5. D. D’Ambrosio, P. Panina-Bordignon, L. Rogge, F. Sinigaglia
      Pages 117-122
    6. F. Sallusto, B. Palermo, A. Hoy, A. Lanzavecchia
      Pages 123-129
  4. Chromosomal Translocations, DNA Rearrangement and Somatic Hypermutations

    1. Front Matter
      Pages 139-139
    2. H. Jacobs, A. Puglisi, K. Rajewsky, Y. Fukita
      Pages 149-159
    3. E. Hilgenfeld, H. Padilla-Nash, E. Schröck, T. Ried
      Pages 169-174
    4. J. F. Mushinski, J. Hanley-Hyde, G. J. Rainey, T. I. Kuschak, C. Taylor, M. Fluri et al.
      Pages 183-192
    5. J. Shaughnessy, B. Barlogie
      Pages 199-203
    6. T. Szczepański, M. J. Pongers-Willemse, A. W. Langerak, J. J. M. van Dongen
      Pages 205-215
    7. W. M. Aarts, R. J. Bende, S. T. Pals, C. J. M. van Noesel
      Pages 217-224
  5. Biology of Lymphomagenesis, B-CLL, Autoimmunity

    1. Front Matter
      Pages 233-233
    2. C. S. Rabkin
      Pages 235-240
    3. A. Alfarano, P. Circosta, A. Vallario, C. Camaschella, S. Indraccolo, A. Amadori et al.
      Pages 241-248
    4. H. C. Morse III, C.-F. Qi, L. Tadesse-Heath, S. K. Chattopadhyay, J. M. Ward, A. Coleman et al.
      Pages 249-255
    5. R. Dalla-Favera, A. Migliazza, C.-C. Chang, H. Niu, L. Pasqualucci, M. Butler et al.
      Pages 257-265
    6. N. Ibnou-Zekri, T. J. Vyse, S. J. Rozzo, M. Iwamoto, T. Kobayakawa, B. L. Kotzin et al.
      Pages 275-281
    7. R. C. Hsueh, A. K. Hammill, R. Marches, J. W. Uhr, R. H. Scheuermann
      Pages 299-305
    8. U. Zimber-Strobl, L. Strobl, H. Höfelmayr, B. Kempkes, M. S. Staege, G. Laux et al.
      Pages 315-321
  6. Myeloma, Plasmacytomas and Related Subjects

    1. Front Matter
      Pages 323-323
    2. K. Nilsson, P. Georgii-Hemming, H. Spets, H. Jernberg-Wiklund
      Pages 325-333
    3. B. Klein, X. Y. Li, Z. Y. Lu, M. Jourdan, K. Tarte, J. Brochier et al.
      Pages 335-341
    4. Shuling Zhang, Beverly A. Mock
      Pages 363-368

About these proceedings


Workshops on the mechanisms of B cell neoplasia have been organized alternatively in Bethesda and Basel since 1983. Prog­ ress in our understanding of the development and responses of B lymphocytes is presented and discussed with the aim and hope to understand what might go wrong when B lymphocytes are transformed into malignant cells. Such knowledge might lead to better diagnosis, prevention and even cure of these terri­ ble diseases. The presentations at the Bethesda workshops are published as papers in volumes of Current Topics in Microbiol­ ogy and Immunology, while the presentations and discussions in Basel were transcribed and published in Editions Roche. For the first time, a Basel workshop (held 4th-6th October 1998) that has been recorded and, in part, transcribed is being published as papers and discussions within Current Topics. This volume is the latest of a long series which documents the excitements of ground-breaking discoveries as well as the frustrations of our inability to fully understand the mechanisms leading to B cell neoplasia. The papers at the workshop are presented when possible in the sequence in which they were given. However, to facilitate the organization and reading of the book and to highlight gen­ eral topics and themes, the papers are organized into five sec­ tions: I B Cell and Plasma Cell Development II Chemokines and Chemokine Receptors III Chromosomal Translocations, DNA Rearrangements and Somatic Hypermutations IV Biology of Lymphomagenesis, B-CLL, Autoimmunity V Myeloma, Plasmacytomas and Related Subjects.


AIDS Chemokine DNA apoptosis autoimmunity bacteria cell immunity leukemia lymphocytes lymphoma mutagen pathogenesis prevention virus

Editors and affiliations

  • Fritz Melchers
    • 1
  • Michael Potter
    • 2
  1. 1.Basel Institute for ImmunologyBaselSwitzerland
  2. 2.Laboratory of Genetics Building 37, Room 2B04National Cancer Institute National Institutes of HealthBethesdaUSA

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 1999
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-642-64283-8
  • Online ISBN 978-3-642-60162-0
  • Series Print ISSN 0070-217X
  • Buy this book on publisher's site