The Proteasome — Ubiquitin Protein Degradation Pathway

  • Peter Zwickl
  • Wolfgang Baumeister

Part of the Current Topics in Microbiology and Immunology book series (CT MICROBIOLOGY, volume 268)

Table of contents

  1. Front Matter
    Pages i-ix
  2. C. Volker, A. N. Lupas
    Pages 1-22
  3. P. Zwickl
    Pages 23-41
  4. M. H. Glickman, V. Maytal
    Pages 43-72
  5. C. P. Hill, E. I. Masters, F. G. Whitby
    Pages 73-89
  6. G. Niedermann
    Pages 91-136
  7. Back Matter
    Pages 209-213

About this book


This volume gives a complete overview of the structure and function of the proteasome, its regulators and inhibitors, and its cellular importance, in conjunction with the ubiquitin system, for the degradation of regulatory proteins and the generation of immunogenic peptides. The topics range from the molecular evolution of the proteasome and its associated activators, the proteasome in the immune response, to proteasome inhibitors.


Cellular proteolysis cognition evolution immunology molecular evolution peptides proteasome inhibitor proteasomes protein proteins ubiquitin system

Editors and affiliations

  • Peter Zwickl
    • 1
  • Wolfgang Baumeister
    • 1
  1. 1.Department of Molecular Structural BiologyMax-Planck-Institute for BiochemistryMartinsriedGermany

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 2002
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-642-63971-5
  • Online ISBN 978-3-642-59414-4
  • Series Print ISSN 0070-217X
  • Buy this book on publisher's site