Shock, Sepsis, and Organ Failure

Scavenging of Nitric Oxide and Inhibition of its Production

  • Günther Schlag
  • Heinz Redl

Table of contents

  1. Front Matter
    Pages I-XIV
  2. K. Träger, K. M. Rieger, B. Šantak, P. Radermacher
    Pages 69-91
  3. R. T. Villavicencio, B. G. Harbrecht, T. R. Billiar
    Pages 93-118
  4. P. M. Kochanek, E. H. Sinz, R. S. B. Clark, C. E. Dixon, M. J. Bell, D. W. Marion
    Pages 145-161
  5. E. R. Werner, K. Schmidt, G. Werner-Felmayer, B. Mayer
    Pages 261-271
  6. S. R. Fischer, D. L. Traber
    Pages 273-293

About these proceedings


At the Sixth Wiggers Bernard Conference, a group of scientists from various fields discussed new findings relating to nitric oxide synthase inhibitor in shock, sepsis, and organ failure. This meeting was dedicated to the presentation and discussion of positive and negative findings related to the use of NOS inhibitors, the issue of specific and non-specific inhibitors and the role of nitric oxide-oxygen radical interactions. Both experimental and clinical data were presented in the trauma and sepsis field. With appropriate dosing and timing the use of NOS inhibitors seems to be beneficial at least in severe sepsis situations, but some inhibitors and overdosing can be potentially dangerous.


Infusion Sepsis Trauma inflammation shock

Editors and affiliations

  • Günther Schlag
    • 1
  • Heinz Redl
    • 1
  1. 1.Ludwig-Boltzmann-Institut für experimentelle und klinische TraumatologieWienAustria

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 1999
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-642-63672-1
  • Online ISBN 978-3-642-58630-9
  • Buy this book on publisher's site