Immunoreceptor Tyrosine-based Inhibition Motifs

  • Marc Daëron
  • Eric Vivier

Part of the Current Topics in Microbiology and Immunology book series (CT MICROBIOLOGY, volume 244)

Table of contents

  1. Front Matter
    Pages I-VII
  2. M. Huber, C. D. Helgason, J. E. Damen, M. P. Scheid, V. Duronio, V. Lam et al.
    Pages 29-41
  3. J. C. Cambier, D. Fong, I. Tamir
    Pages 43-55
  4. R. J. Cornall, C. C. Goodnow, J. G. Cyster
    Pages 57-68
  5. A. Moretta, C. Bottino, R. Millo, R. Biassoni
    Pages 69-84
  6. H. Kubagawa, M. D. Cooper, C. C. Chen, L. H. Ho, T. L. Alley, V. Hurez et al.
    Pages 137-149
  7. A. Cambiaggi, M. Lucas, E. Vivier, F. Vély
    Pages 169-176
  8. Back Matter
    Pages 177-182

About this book


Novel molecular motifs named Immunoreceptor Tyrosine-based Inhibition Motifs (ITIMs) have recently been recognized in the intracytoplasmic domains of a still-increasing number of receptors which control cell activation and proliferation. Research on ITIM-bearing molecules has developed exponentially during the last three years, generating new concepts with important consequences in basic research and with exciting potential clinical applications. The present volume contains 15 reviews written by authors who all made significant contributions to the identification of ITIM-bearing molecules and the study of their biological properties. It constitutes the first synthesis ever published that is specifically devoted to this emerging topic.


Activation Antigen Endoplasmatisches Reticulum biology cell cytoplasm immunoglobulin immunoregulation proliferation regulation signal transduction

Editors and affiliations

  • Marc Daëron
    • 1
  • Eric Vivier
    • 2
  1. 1.Laboratoire d’Immunologie Cellulaire et Clinique INSERM U.255Institut CurieParisFrance
  2. 2.Centre d’Immunologie INSERM-CNRS de Marseille LuminyInstitut Universitaire de FranceMarseille Cedex 9France

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 1999
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-642-63634-9
  • Online ISBN 978-3-642-58537-1
  • Series Print ISSN 0070-217X
  • Buy this book on publisher's site