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Hydroxy-Pyridones as Antifungal Agents with Special Emphasis on Onychomycosis

  • Sam Shuster
Conference proceedings

Table of contents

  1. Front Matter
    Pages I-X
  2. W. Schalla, K. Kraemer, R. Pooth
    Pages 18-32
  3. M. A. J. Allevato
    Pages 39-42
  4. S. A. Burova
    Pages 43-44
  5. B. B. Abrams, R. J. Cherill, R. Ramaswamy, H. I. Katz
    Pages 45-50
  6. A. Stary, S. Torma, P. G. Sator
    Pages 81-90
  7. T. R. Einarson, P. I. Oh, N. Shear
    Pages 91-95

About these proceedings

Introduction

This book summarizes the results of two symposia held on hydroxy-pyridones as antifungal agents organized on the occasion of the International Summit on Cutaneous Antifungal Therapy 1996 in Vancouver and the 19th World Congress of Dermatology 1997 in Sydney. Some of the papers deal with the basic mechanisms of action and how these translate into product features, e.g. activity spectrum. Other papers describe the unique properties of hydroxy-pyridones, such as high penetration into and through keratinic tissues or their activity as dual inhibitor on 5-lipoxygenase and cyclooxygenase which leads to a remarkable antiinflammatory effect. Last but not least various accounts are given which show how this unique product profile aids the treatment of various fungal diseases, especially onychomycosis.

Keywords

Antifungal Agents Ciclopirox Dermatitis Mycosis Mykosen Onychomycosis Pilzerkrankungen epidemiology infection research therapy

Editors and affiliations

  • Sam Shuster
    • 1
  1. 1.Department of Dermatology Framlington PlaceUniversity of Newcastle upon TyneNewcastle upon TyneEngland

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-642-58401-5
  • Copyright Information Springer-Verlag Berlin Heidelberg 1999
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-540-65494-0
  • Online ISBN 978-3-642-58401-5
  • Buy this book on publisher's site