Biological Effects of Dietary Restriction

  • Lawrence Fishbein
Conference proceedings

Part of the ILSI Monographs book series (ILSI MONOGRAPHS)

Table of contents

  1. Front Matter
    Pages i-xvi
  2. Feeding Regimens and Diets

  3. Effects of Dietary Restriction on Toxicological Endpoints

  4. Effects and Mechanisms of Dietary Restriction: Physiological Consequences

  5. Effects and Mechanisms of Dietary Restriction: Biochemical Consequences

    1. Front Matter
      Pages 183-183
    2. B. P. Yu, D.-W. Lee, J.-H. Choi
      Pages 191-197
    3. R. J. Feuers, D. A. Casciano, J. G. Shaddock, J. E. A. Leakey, P. H. Duffy, R. W. Hart et al.
      Pages 198-206
    4. J. E. A. Leakey, J. J. Bazare, J. R. Harmon, R. J. Feuers, P. H. Duffy, R. W. Hart
      Pages 207-216
  6. Models for Dietary Restriction Research

    1. Front Matter
      Pages 227-227
    2. D. L. Snyder, B. S. Wostmann, M. Pollard
      Pages 238-244
    3. D. E. Harrison, J. R. Archer, B. Kent
      Pages 264-286
    4. G. S. Roth, D. K. Ingram, R. G. Cutler
      Pages 305-317
  7. Impact of Dietary Restriction on Bioassays and Recommendations for Future Research

    1. Front Matter
      Pages 319-319
    2. C. J. Henry, D. B. Clayson, G. N. Rao, F. J. C. Roe, R. J. Scheuplein, D. E. Stevenson
      Pages 321-336
  8. Back Matter
    Pages 337-354

About these proceedings


How does dietary restriction affect the physiological and biochemical state of laboratory animals? How will the present conclusions affect further research? What are the implications for human health and safety assessment? These are the main questions asked in this book by leading international researchers. After a first look at feeding regimens and diets of laboratory animals, the book elaborates on a variety of age-associated toxicological and pathological endpoints including tumor development. The following sections detail the underlying mechanisms which may induce the broad spectrum of physiological and biochemical changes. This summary of current multidisciplinary research will enhance understanding of the practical applications and implications of dietary restriction.


Alterungsprozeß DNA Ernährung Glucocorticoid Krebs cancer dietary restriction enzyme enzymes metabolism research tissue toxicity toxicology tumor

Editors and affiliations

  • Lawrence Fishbein
    • 1
  1. 1.USA

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 1991
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-642-63494-9
  • Online ISBN 978-3-642-58181-6
  • Buy this book on publisher's site