Thermoradiotherapy and Thermochemotherapy

Biology, Physiology, Physics

  • M. Heinrich Seegenschmiedt
  • Peter Fessenden
  • Clare C. Vernon

Part of the Medical Radiology book series (MEDRAD)

Table of contents

  1. Front Matter
    Pages I-XII
  2. Historical Review

    1. Front Matter
      Pages 1-1
    2. M. H. Seegenschmiedt, C. C. Vernon
      Pages 3-44
  3. Biological Principles

    1. Front Matter
      Pages 45-45
    2. P. Burgman, A. Nussenzweig, G. C. Li
      Pages 75-87
    3. M. W. Dewhirst
      Pages 123-136
  4. Pathophysiological Mechanisms

    1. Front Matter
      Pages 137-137
    2. C. W. Song, I. B. Choi, B. S. Nah, S. K. Sahu, J. L. Osborn
      Pages 139-156
    3. P. W. Vaupel, D. K. Kelleher
      Pages 157-176
  5. Physical Principles and Engineering

    1. Front Matter
      Pages 191-191
    2. P. Wust, M. Seebass, J. Nadobny, R. Felix
      Pages 219-251
    3. K. Hynynen
      Pages 253-277
    4. P. R. Stauffer, C. J. Diederich, M. H. Seegenschmiedt
      Pages 279-320
    5. D. I. Roos, M. H. Seegenschmiedt, B. Sorbe
      Pages 321-329
    6. F. M. Waterman
      Pages 331-360
    7. J. C. Bolomey, D. Le Bihan, S. Mizushina
      Pages 361-379
    8. C. J. Schneider, R. Olmi, J. D. P. van Dijk
      Pages 381-397
    9. K. D. Paulsen
      Pages 399-423
    10. J. Mooibroek, J. Crezee, J. J. W. Lagendijk
      Pages 425-437
    11. J. J. W. Lagendijk, J. Crezee, J. Mooibroek
      Pages 439-451
    12. A. G. Visser, G. C. van Rhoon
      Pages 453-472
  6. Back Matter
    Pages 473-483

About this book


Hyperthermia has been found to be of great benefit in combination with radiation therapy or chemotherapy in the management of patients with difficult and com­ plicated tumor problems. It has been demonstrated to increase the efficacy, of ionising radiation when used locally but also has been of help in combination with systemic chemotherapy where hyperthermia is carried out to the total body. Problems remain with regard to maximizing the effects of hyperthermia as in­ fluenced by blood flow, heat loss, etc. The present volume defines the current knowledge relative to hyperthermia with radiation therapy and/or chemotherapy, giving a comprehensive overview of its use in cancer management. Philadelphia/Hamburg, June 1995 L.W. BRADY H.-P. HEILMANN Preface In an attempt to overcome tumor resistance, hypoxia, or unfavorable tumor condi­ tions, oncological research has come to focus on gene therapy, immunotherapy, new cytotoxic agents, and increasingly sophisticated radiotherapy. Radiation research has been directed towards heavy particle therapy and modification of the radiation response by either protecting or sensitizing agents. Improved dose localization using rotational or conformal strategies has also been implemented. Recently, changes in radiation fractionation schedules have shown promise of better results. Hyperthermia in cancer therapy can be viewed similarly as another means to increase the sensitivity of tumors to radio- and chemotherapy.


Chemotherapie Hyperthermia techniques Krebstherapie Onkologie Strahlentherapie Tumor cancer chemotherapy dosimetry hyperthermia physiology radiation radiotherapy thermotherapy ultrasound

Editors and affiliations

  • M. Heinrich Seegenschmiedt
    • 1
  • Peter Fessenden
    • 2
  • Clare C. Vernon
    • 3
  1. 1.Strahlentherapeutische KlinikUniversität Erlangen-NürnbergErlangenGermany
  2. 2.Radiation Oncology Physics DivisionStanford University Medical CenterStanfordUSA
  3. 3.Department of Clinical OncologyHammersmith HospitalLondonUK

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 1995
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-642-63382-9
  • Online ISBN 978-3-642-57858-8
  • Series Print ISSN 0942-5373
  • Buy this book on publisher's site