Development and Regenerative Capacity of Descending Supraspinal Pathways in Tetrapods: A Comparative Approach

  • H. J. ten Donkelaar

Part of the Advances in Anatomy Embryology and Cell Biology book series (ADVSANAT, volume 154)

Table of contents

  1. Front Matter
    Pages I-IX
  2. H. J. ten Donkelaar
    Pages 1-4
  3. H. J. ten Donkelaar
    Pages 5-8
  4. H. J. ten Donkelaar
    Pages 15-25
  5. H. J. ten Donkelaar
    Pages 103-112
  6. H. J. ten Donkelaar
    Pages 113-115
  7. Back Matter
    Pages 117-145

About this book


In this treatise, current knowledge on the neurogenesis, axonal outgrowth, synaptogenesis, and regenerative capacity of descending supraspinal pathways in tetrapods is discussed. Although emphasis is on the clawed toad, Xenopus laevis, chicken embryos, opossum and rodent data, also the data available for primates including man are presented. It will be shown that 1) the outgrowth of descending supraspinal pathways is the result of a coordinated program; 2) the pattern of early descending axonal tracts is similar in all vertebrate groups; 3) the formation of descending supraspinal pathways occurs according to a developmental sequence; 4) the earliest descending supraspinal fibers arrive in a rather immature spinal cord, and 5) the regenerative capacity of descending supraspinal pathways depends on the developmental stage the particular pathways arise.


Locomotor patterns brainstem descending pathways motor system phylogenetic constancy reticulospinal neurons rubrospinal tract tetrapods

Authors and affiliations

  • H. J. ten Donkelaar
    • 1
  1. 1.Department of NeurologyUniversity Hospital Nijmegen and The Nijmegen Institute for Neurosciences University of NijmegenNijmegenThe Netherlands

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 2000
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-540-66466-6
  • Online ISBN 978-3-642-57125-1
  • Series Print ISSN 0301-5556
  • Series Online ISSN 2192-7065
  • Buy this book on publisher's site