Apoptosis and Its Modulation by Drugs

  • Ross G. Cameron
  • George Feuer

Part of the Handbook of Experimental Pharmacology book series (HEP, volume 142)

Table of contents

  1. Front Matter
    Pages I-XXV
  2. D. Pessayre, G. Feldmann, D. Haouzi, D. Fau, A. Moreau, M. Neuman
    Pages 59-108
  3. J. Savill, C. Bebb
    Pages 151-177
  4. R. Cameron, L. Zhang
    Pages 179-196
  5. A.-M. Woodgate, M. Dragunow
    Pages 197-233
  6. C. Thiede, T.D. Kim, A. Neubauer
    Pages 235-255
  7. Y. Delneste, E. Roelandts, J.-Y. Bonnefoy, P. Jeannin
    Pages 257-273
  8. G. Bauer, S. Dormann, I. Engelmann, A. Schulz, M. Saran
    Pages 275-318
  9. M. Neuman, R. Cameron, N. Shear
    Pages 343-355
  10. H.-U. Simon
    Pages 357-374
  11. T. Itoh, M. Nakamura, H. Yagi, H. Soga, T. Ishii
    Pages 375-397
  12. T. Defrance, M. Berard, M. Casamayor-Palleja
    Pages 399-427
  13. Back Matter
    Pages 473-478

About this book


Apoptosis is a fascinating concept for the basic scientist. This is not only because of the multifaceted variety of proposed and discovered mechanisms, but because apoptosis represents a fundamental pathway for cell renewal. The study of apoptosis has resulted in an array of discoveries on signal transduc­ tion and downstream effects that have facilitated and advanced many fields in biology, including research on cancer and other diseases. Thus, the apoptotic process can be viewed as the largest effort of the scientific community to understand how cells work and tissues assemble or remodel. The most direct consequence of this accumulated knowledge is a greater understanding of disease and pathological mechanisms. The end result of these efforts will be significant contributions to health and the adoption of new, never anticipated, therapeutic approaches. This book represents the summation of considerable effort from a significant group of contributors from all over the world as well as from its editors. In this fashion, many viewpoints have been collected and SUbjected to thorough academic discussion. The concepts contained in this medically important volume will stimulate and renew the ideas of scientists and indeed, will generate additional work to advance biological knowledge even further. The emphasis of this volume cements what has been established, adds what has not been explored fully, and creates a fertile ground for further hypotheses that will lead to a more complete understanding of the apoptotic process.


AIDS Antigen Apoptosis Drugs Programmed cell death Regulation Zelltod cells gene therapy tissue

Editors and affiliations

  • Ross G. Cameron
    • 1
  • George Feuer
    • 2
  1. 1.Department of Pathology Toronto Hospital, General DivisionUniversity of TorontoTorontoCanada
  2. 2.Banting Institute Department of Clinical BiochemistryUniversity of TorontoTorontoCanada

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 2000
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-642-63025-5
  • Online ISBN 978-3-642-57075-9
  • Series Print ISSN 0171-2004
  • Series Online ISSN 1865-0325
  • Buy this book on publisher's site