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Genes and Resistance to Disease

  • V. Boulyjenkov
  • K. Berg
  • Y. Christen

Table of contents

  1. Front Matter
    Pages I-XII
  2. F. Schächter
    Pages 1-7
  3. S. J. O’Brien, M. Dean, M. Smith, C. Winkler, G. W. Nelson, M. P. Martin et al.
    Pages 9-17
  4. M. P. Soares, C. Ferran, K. Sato, K. Takigami, J. Anrather, Y. Lin et al.
    Pages 91-103
  5. L. Luzzatto
    Pages 105-119
  6. I. M. Verma, L. Naldini, T. Kafri, H. Miyoshi, M. Takahashi, U. Blömer et al.
    Pages 147-157
  7. V. I. Ivanov
    Pages 159-168
  8. Back Matter
    Pages 179-180

About these proceedings

Introduction

The advances in human genetics that have ocurred during the past 20 years have revolutionized our knowledge of the role played by inheritance in health and disase. It is clear that our DNA determines not only the emergence of catastrophic single-gene disorders, which affect millions of persons worldwide, but also interacts with environments to predispose individuals to cancer, allergy, hypertension, heart disease, diabetes, psychiatric disorders and even to some infectious diseases. Overall, the study of longevity and the demonstration of genes favouring a long lifespan suggest that such protective systems exist. In recent years, the study of genetic polymorphisms has made clear that some alleles have beneficial effects. These discoveries can substantially improve our understanding of the interactions between genetics and the environment, between pathogenetic mechanisms and new treatments.

Keywords

Allele Alzheim's Disease DNA Malaria resistance gene therapy genes genetics neurodegenerative diseases

Editors and affiliations

  • V. Boulyjenkov
    • 1
  • K. Berg
    • 2
    • 3
  • Y. Christen
    • 4
  1. 1.Human Genetics Department of Noncommunicable Disease PreventionWorld Health OrganizationSwitzerland
  2. 2.Institute of Medical GeneticsUniversity of OsloOsloNorway
  3. 3.Department of Medical GeneticsUllevål University HospitalOsloNorway
  4. 4.Fondation IPSENPour la Recherche ThérapeutiqueParis Cedex 16France

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-642-56947-0
  • Copyright Information Springer-Verlag Berlin Heidelberg 2000
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-642-63086-6
  • Online ISBN 978-3-642-56947-0
  • Buy this book on publisher's site