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The Skin and Gene Therapy

  • Ulrich R. Hengge
  • Beatrix Volc-Platzer
Book

Table of contents

  1. Front Matter
    Pages I-XIX
    PDF

  2. Basic Aspects

    1. Front Matter
      Pages 1-1
      PDF
    2. The Epidermal Barrier and Strategies for Surmounting It: An Overview
      G. K. Menon, P. M. Elias
      Pages 3-26
    3. Stem Cells, Differentiation and Renewal Kinetics of Keratinocytes: Implications for Cutaneous Gene Therapy
      J. R. Bickenbach
      Pages 27-34
    4. Relevant Animal Models for Skin Gene Therapy
      M. J. Arin, T. Cao, T. R. Berton, Z. Zhou, X. J. Wang, D. R. Roop
      Pages 35-51
    5. Nonviral Gene Transfer into the Skin
      B. Volc-Platzer, U. R. Hengge, A. Udvardi
      Pages 53-65
    6. Safety and Pharmacokinetics of Naked Plasmid DNA: Studies on Dissemination and Ectopic Expression
      U. R. Hengge, B. Dexling, A. Udvardi, B. Volc-Platzer, A. Mirmohammdsadegh
      Pages 67-80
    7. Uptake of DNA by Keratinocytes
      U. R. Hengge, E. Tschakarjan, A. Mirmohammdsadegh, M. Goos, H. E. Meyer
      Pages 81-94

  3. Treatment of Skin Diseases

    1. Front Matter
      Pages 95-95
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    2. Gene Therapy of Inherited Skin Diseases
      G. Meneguzzi, J. Vailly
      Pages 97-116
    3. Gene Transfer Strategies in Tissue Repair
      S. A. Eming, J. M. Davidson, T. Krieg
      Pages 117-137

  4. Systemic Effects of Skin Gene Therapy

    1. Front Matter
      Pages 139-139
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    2. The Use of Skin-Directed Gene Therapy in the Treatment of Systemic Diseases
      T. G. Jensen, K. G. Csaky
      Pages 141-154
    3. Keratinocyte Gene Therapy Using Cytokine Genes
      D. Sawamura
      Pages 155-173

  5. Genetic Vaccination Using the Skin

    1. Front Matter
      Pages 175-175
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    2. Principles of Genetic Immunization
      D. J. Lee, K. Takabayashi, M. Corr, E. Raz
      Pages 177-200
    3. Systematic Modulation of Immune Responses by CpG DNA
      A. M. Krieg
      Pages 201-218
    4. Genetic and Dendritic Cell Vaccination as a Novel Therapy for Melanoma
      D. Schadendorf, A. Paschen, Y. Sun
      Pages 219-243
    5. Molecular Strategies Interfering with Tumor Progression of Melanoma and Improving Anti-Tumor Immunity
      A. Schneeberger, M. Goos, G. Stingl, S. N. Wagner
      Pages 245-273
    6. Prophylactic and Therapeutic DNA Vaccines Against Infectious Disease
      J. E. Kallman, H. C. Maguire Jr., J. S. Yang, J. J. Kim, D. B. Weiner
      Pages 275-294
  6. Back Matter
    Pages 295-301
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About this book

Keywords

DNA cell cytokine dermatology diseases gene therapy gene transfer infectious disease melanoma stem cells therapy tissue tumor tumor progression vaccine

Editors and affiliations

  • Ulrich R. Hengge
    • 1
  • Beatrix Volc-Platzer
    • 2
  1. 1.Department of Dermatology, Venerology and AllergologyUniversity of EssenEssenGermany
  2. 2.Division of Immunology, Allergy and Infectious Diseases, Department of DermatologyUniversity of Vienna Medical SchoolViennaAustria

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-642-56441-3
  • Copyright Information Springer-Verlag Berlin ¿ Heidelberg 2001
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-642-63093-4
  • Online ISBN 978-3-642-56441-3
  • Buy this book on publisher's site