Pathogenicity Islands and the Evolution of Pathogenic Microbes

Volume I

  • Jörg Hacker
  • James B. Kaper

Part of the Current Topics in Microbiology and Immunology book series (CT MICROBIOLOGY, volume 264/2)

Table of contents

  1. Front Matter
    Pages I-XVII
  2. W. Arber
    Pages 1-14
  3. A. G. Torres, J. B. Kaper
    Pages 31-48
  4. M. Ingersoll, E. A. Groisman, A. Zychlinsky
    Pages 49-65
  5. R. A. Kingsley, A. J. Bäumler
    Pages 67-87
  6. P. P. Reeves, L. Wang
    Pages 109-135
  7. B. Barrett, L. Ebah, I. S. Roberts
    Pages 137-155
  8. U. Dobrindt, U. Hentschel, J. B. Kaper, J. Hacker
    Pages 157-175
  9. F. von Wintzingerode, G. Gerlach, B. Schneider, R. Gross
    Pages 177-199
  10. K. Larbig, C. Kiewitz, B. Tümmler
    Pages 201-211
  11. Back Matter
    Pages 213-231

About this book


It has been known for a number of years that not only pathogenicity islands but also plasmids and bacteriophages are able to carry genes whose products are involved in pathogenic processes. Accordingly, such elements and their products play an important role in pathogenesis due to the intestinal E. coli as well to Shigellae. Another interesting aspect which is reflected in different articles is that genomes evolve by acquisition of new pieces of DNA following gene transfer, but also by genome reduction. Different mechanisms include the deletion of sequences or the elimination of functions by the accumulation of point mutations or rearrangements.


DNA Escherichia coli bacteria fungi gene gene transfer genes genome structure helicobacter pylori microbe microbes pathogenesis pseudomonas resistance yersinia

Editors and affiliations

  • Jörg Hacker
    • 1
  • James B. Kaper
    • 2
  1. 1.Institut für Molekulare InfektionsbiologieUniversität WürzburgWürzburgGermany
  2. 2.Center for Vaccine DevelopmentUniversity of Maryland School of MedicineBaltimoreUSA

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 2002
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-642-62720-0
  • Online ISBN 978-3-642-56031-6
  • Series Print ISSN 0070-217X
  • Buy this book on publisher's site