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Xeno-transplantation

  • Daniel R. Salomon
  • Carolyn Wilson

Part of the Current Topics in Microbiology and Immunology book series (CT MICROBIOLOGY, volume 278)

Table of contents

About this book

Introduction

Xenotransplantation could have an impact on at least three aspects of medicine. The first is as a means of overcoming a severe shortage of human donor organs for the treatment of organ failure. The second aspect relates to the possibility that a xenogeneic organ would not be susceptible to infection by a "human" virus and thus the xenograft might resist injury caused by such viruses. The third and, as of yet, unexplored aspect relates to a means of delivering genes for therapeutic purposes thus overcoming some of the limitations of "conventional" gene therapy.     

Keywords

cross-species infection gene gene therapy hepatitis immune barrier infection infections molecular cloning organ transgenic engineering transplantation virus

Editors and affiliations

  • Daniel R. Salomon
    • 1
  • Carolyn Wilson
    • 2
  1. 1.Department of Molecular and Experimental MedicineThe Scripps Research InstituteLa JollaUSA
  2. 2.Division of Cellular and Gene Therapies Center for Biologics Evaluation and ResearchU.S. Food and Drug AdministrationBethesdaUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-642-55541-1
  • Copyright Information Springer-Verlag Berlin Heidelberg 2003
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-642-62431-5
  • Online ISBN 978-3-642-55541-1
  • Series Print ISSN 0070-217X
  • Buy this book on publisher's site