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DNA Repair

  • Fritz Eckstein
  • David M. J. Lilley

Part of the Nucleic Acids and Molecular Biology book series (NUCLEIC, volume 12)

Table of contents

  1. Front Matter
    Pages I-XI
  2. P. E. Verdemato, P. C. E. Moody
    Pages 1-27
  3. C. D. Mol, S. S. Parikh, T. P. Lo, J. A. Tainer
    Pages 29-69
  4. G. De Murcia, F. Dantzer, C. Trucco, V. Rolli, F. J. Oliver, C. Niedergang et al.
    Pages 83-102
  5. N. Goosen, G. F. Moolenaar, R. Visse, P. van de Putte
    Pages 103-123
  6. E. C. Friedberg, W. J. Feaver, W. Huang, M. S. Reagan, W. A. Ramos, K. Rodriguez et al.
    Pages 125-139
  7. T. Bessho, A. Sancar
    Pages 141-155
  8. R. A. Verhage, M. Tijsterman, P. van de Putte, J. Brouwer
    Pages 157-172
  9. M. O’Driscoll, O. Humbert, P. Karran
    Pages 173-197
  10. P. Schär, J. Jiricny
    Pages 199-247
  11. J. A. Mello, E. E. Trimmer, M. Kartalou, J. M. Essigmann
    Pages 249-274
  12. R. Bowater
    Pages 301-314
  13. Back Matter
    Pages 315-319

About this book

Introduction

DNA is the central repository of genetic information in the cell, yet it is under constant attack by chemical mutagens, radiation and other processes. Cells therefore put a great deal of resources into repairing any damage to this precious store. Mechanisms of DNA repair vary greatly in their level of complexity, from specific reversal mechanisms that involve a single protein, to sequential pathways that require many enzymes. But at the heart of all these mechanisms lie proteins that recognize damage to DNA, raising important questions about how damaged DNA may be distinguished. These recognition processes are now finally yielding their secrets to structural analysis. This volume focuses on DNA repair, with an emphasis on structural data where available.

Keywords

DNA DNA repair Nucleotide base base exision repair cell enzyme enzymes genetics genome nucleotide excision repair protein proteins transcription

Editors and affiliations

  • Fritz Eckstein
    • 1
  • David M. J. Lilley
    • 2
  1. 1.Max-Planck-Institut für Experimentelle MedizinGöttingenGermany
  2. 2.Biochemistry DepartmentUniversity of DundeeDundeeUK

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-642-48770-5
  • Copyright Information Springer-Verlag Berlin Heidelberg 1998
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-642-48772-9
  • Online ISBN 978-3-642-48770-5
  • Series Print ISSN 0933-1891
  • Series Online ISSN 1869-2486
  • Buy this book on publisher's site