Genes and Environment in Cancer

  • Manfred Schwab
  • Hartmut M. Rabes
  • Klaus Munk
  • Hans Peter Hofschneider

Part of the Recent Results in Cancer Research book series (RECENTCANCER, volume 154)

Table of contents

  1. Front Matter
    Pages I-XIV
  2. Key Notes

  3. Risk Assessment and DNA Lesions

    1. Front Matter
      Pages 37-37
    2. H. Bartsch, M. Rojas, K. Alexandrov, A. Risch
      Pages 86-96
    3. E. Dogliotti, P. Hainaut, T. Hernandez, M. D’Errico, D. M. Demarini
      Pages 97-124
  4. DNA Repair and Genetic Susceptibility

    1. Front Matter
      Pages 125-125
    2. M. F. Rajewsky, J. Engelbergs, J. Thomale, T. Schweer
      Pages 127-146
    3. G. Weeda, J. de Boer, I. Donker, J. de Wit, S. B. Winkler, G. T. J. van der Horst et al.
      Pages 147-155
    4. M. A. R. Yuille, L. J. A. Coignet
      Pages 156-173
  5. Induced Chromosome Damage and Cancer

    1. Front Matter
      Pages 175-175
    2. L. Hagmar, S. Bonassi, U. Strömberg, Z. Mikoczy, C. Lando, I.-L. Hansteen et al.
      Pages 177-184
    3. T. W. Glover
      Pages 185-199
    4. K. Huebner, T. Druck, Z. Siprashvili, C. M. Croce, A. Kovatich, P. A. McCue
      Pages 200-215
    5. M. Debatisse, A. Coquelle, F. Toledo, G. Buttin
      Pages 216-226
  6. Genetic Susceptibility and Environmental Exposure: “The RET Paradigm”

    1. Front Matter
      Pages 227-227

About these proceedings

Introduction

Different cancer types can result from a multiplicity of environmental and genetic factors. Molecular epidemiology has focused recently on elucidating relationships between particular genetic alterations and the type of environmental exposure. Several genes have been identified as strong determinants for a number of cancer types. The incomplete penetrance often evidenced by mutations of these genes has raised the possibility that additional endogenous or exogenous determinants are involved in cancer development or suppression. The major aim of this book is to present an integrated view of environmental, epidemiological, and genetic determinants that contribute to cancer susceptibility and progression.

Keywords

DNA Genetik Termination breast cancer cancer cancer therapy carcinogenesis carcinoma chromosome colorectal cancer epidemiology genes genetics molecular genetics tumor

Editors and affiliations

  • Manfred Schwab
    • 1
  • Hartmut M. Rabes
    • 2
  • Klaus Munk
    • 3
  • Hans Peter Hofschneider
    • 4
  1. 1.Abteilung ZytogenetikDeutsches KrebsforschungszentrumHeidelbergGermany
  2. 2.Pathologisches InstitutUniversität MünchenMünchenGermany
  3. 3.Deutsches KrebsforschungszentrumHeidelbergGermany
  4. 4.Max-Planck-Institut für BiochemieMartinsriedGermany

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-642-46870-4
  • Copyright Information Springer-Verlag Berlin Heidelberg 1998
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-642-46872-8
  • Online ISBN 978-3-642-46870-4
  • Series Print ISSN 0080-0015
  • About this book