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Neurobiology of Opioids

  • Osborne F. X. Almeida
  • Toni S. Shippenberg

Table of contents

  1. Front Matter
    Pages I-XXII
  2. General Aspects

    1. Front Matter
      Pages 1-1
    2. M. K.-H. Schafer, R. Day, S. J. Watson, H. Akil
      Pages 53-71
  3. Opioid Receptor Biochemistry and Signal Transduction

  4. CNS Opioidergic Systems: Distribution and Modulation

    1. Front Matter
      Pages 167-167
    2. B. J. Morris
      Pages 185-197
    3. G. Burns, K. E. Nikolarakis
      Pages 199-211
  5. Functional Aspects

    1. Front Matter
      Pages 227-227
    2. R. Przewłocki, B. Przewłocka, W. Lasoń
      Pages 229-243
    3. M. J. Millan, E. Weihe, A. C. Czlonkowski
      Pages 245-260
    4. C. Stein
      Pages 273-285
    5. O. F. X. Almeida, D. G. Pfeiffer
      Pages 301-330
    6. A. Pfeiffer
      Pages 351-362
    7. H. M. Emrich, C. Schmauss
      Pages 363-367
  6. Opioid Tolerance and Dependence

  7. Epilogue

    1. Front Matter
      Pages 441-441
  8. Back Matter
    Pages 447-456

About this book

Introduction

Dedicated to Professor Albert Herz, a leading investigator in opioid research, this book provides comprehensive information on the biology of exogenous and endogenous opioids. Contributions by experts in the field discuss recent advances and provide systematic, up-to-date reviews of the physiology and pharmacology of opioids, as well as on the cellular and molecular mechanisms underlying opioid actions. In recognition of the diverse methodologies now available to researchers, each chapter details the approaches used to address a specific issue and provides an in-depth analysis of the data obtained by these various experimental approaches. The clinical relevance of recent findings, as well as future directions, in opioid research are also discussed. This volume thus represents a timely and invaluable sourcebook for researchers, clinicians, and students interested in opioids and peptidergic systems.

Keywords

CNS Nucleotide Rezeptoren Zentralnervensystem biochemistry biology brain gene expression neurobiology neuropeptides opioid physiology receptor research signal transduction

Editors and affiliations

  • Osborne F. X. Almeida
    • 1
  • Toni S. Shippenberg
    • 2
  1. 1.Department of NeuroendocrinologyMax Planck Institute for PsychiatryMünchen 40Germany
  2. 2.Department of NeuropharmacologyMax Planck Institute for PsychiatryMartinsriedGermany

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-642-46660-1
  • Copyright Information Springer-Verlag Berlin Heidelberg 1991
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-642-46662-5
  • Online ISBN 978-3-642-46660-1
  • Buy this book on publisher's site