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Bradykinin, Kallidin and Kallikrein

  • Ervin G. Erdös
  • Anne F. Wilde

Table of contents

  1. Front Matter
    Pages I-XIX
  2. Introduction

  3. Methods Used in Kinin Research

  4. Kininogenases

    1. V. Eisen, W. Vogt
      Pages 82-130
    2. Marion E. Webster
      Pages 131-155
    3. J. L. Prado
      Pages 156-192
    4. Tomoji Suzuki, Sadaaki Iwanaga
      Pages 193-212
    5. Rosmarie Vogel, Eugen Werle
      Pages 213-249
  5. Kininogens

    1. E. Habermann
      Pages 250-288
  6. Kininases

    1. E. G. Erdös, H. Y. T. Yang
      Pages 289-323
  7. Kinins

    1. Physiological and Pharmacological Actions

      1. E. Schröder
        Pages 324-350
      2. Gerhard A. Brecher, Günther F. Brobmann
        Pages 351-361
      3. F. J. Haddy, T. E. Emerson Jr., J. B. Scott, R. M. Daugherty Jr.
        Pages 362-384
      4. H. O. J. Collier
        Pages 409-420
      5. Edward J. Walaszek
        Pages 430-433
    2. Pathological Role

      1. Désirée Armstrong
        Pages 434-481
      2. Federigo Sicuteri
        Pages 482-515
      3. G. P. Lewis
        Pages 516-530
      4. Jocelyn Spragg, R. C. Talamo, K. F. Austen
        Pages 531-548
      5. Ervin G. Erdös, Anne F. Wilde
        Pages 549-549
  8. Urinary Kinins

    1. Ervin G. Erdös
      Pages 579-584
  9. Non-Mammalian Kinins

    1. M. Schachter
      Pages 585-588
    2. John J. Pisano
      Pages 589-595
  10. Summary of Literature Published in Various Languages

  11. Back Matter
    Pages 659-768

About this book

Introduction

Bradykinin is frequently referred to as an elusive substance; the editor of a comprehensive volume dealing with kinins thus has a difficult task. The com­ plexity of the issues calls for a large number of contributors who approach the topics from the various angles that are dictated by the sometimes divergent views of the individuals. The editor saw no reason to prescribe the mode of presentation, which was left to the authors and accounts for the variety of approaches. Contributors from nine countries were asked to participate in the volume. The chapters were organized to present, first, the history of the discoveries and methods of approach to kinin research. Then follows a discussion of the enzymes that release kinins, their substrates, and other enzymes that inactivate the peptides. If the release of kinin is important, then the inhibition of the releasing enzymes is of obvious interest and is described. Since the measurement of kinin­ ogen levels in blood has been frequently used as an indicator of kinin liberation, in addition to a separate chapter, kininogens are also mentioned where the functions of kinins are discussed. The conclusions drawn from establishing structure-action relationships for many analogs and the actions of kinins are indicated and summarized.

Keywords

Respiration antibody assessment central nervous system chemistry chromatography heart inflammation kidney nervous system pathology pharmacodynamics pharmacology research therapy

Editors and affiliations

  • Ervin G. Erdös
    • 1
  • Anne F. Wilde
  1. 1.Department of PharmacologyUniversity of Oklahoma Medical CenterOklahoma CityUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-642-46222-1
  • Copyright Information Springer-Verlag Berlin Heidelberg 1970
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-642-46224-5
  • Online ISBN 978-3-642-46222-1
  • Series Print ISSN 0171-2004
  • Series Online ISSN 1865-0325
  • Buy this book on publisher's site