Pathologies of Calcium Channels

  • Norbert Weiss
  • Alexandra Koschak

Table of contents

  1. Front Matter
    Pages i-xviii
  2. Pathologies of Voltage-Gated Calcium Channels

    1. Front Matter
      Pages 1-1
    2. Daniela Pietrobon
      Pages 3-25
    3. Stephanie Schorge, Kinya Ishikawa
      Pages 27-45
    4. Alexandra Koschak, Alexandra Pinggera, Klaus Schicker, Jörg Striessnig
      Pages 47-75
    5. Stuart M. Cain, Michael E. Hildebrand, Terrance P. Snutch
      Pages 77-96
    6. Amaury Francois, Anne Pizzoccaro, Sophie Laffray, Emmanuel Bourinet
      Pages 115-133
    7. Emma Matthews, Michael G. Hanna
      Pages 135-149
    8. Viktor Yarotskyy, Robert T. Dirksen
      Pages 151-165
    9. Julien Fauré, Joël Lunardi, Nicole Monnier, Isabelle Marty
      Pages 167-187
    10. Paul W. Wirtz, Maarten J. Titulaer, Jan J. G. M. Verschuuren
      Pages 189-204
    11. Pietro Mesirca, Matteo E. Mangoni
      Pages 239-254
    12. Jan Matthes, Stefan Herzig
      Pages 255-275
    13. Maria Beatrice Morelli, Sonia Liberati, Consuelo Amantini, Matteo Santoni, Massimo Nabissi, Valerio Farfariello et al.
      Pages 277-295
    14. Lubica Lacinová, Lucia Lichvárová
      Pages 297-314
  3. Pathologies of Transient Receptor Potential Channels

    1. Front Matter
      Pages 315-315
    2. Shoichi Irie, Takahisa Furukawa
      Pages 317-331

About this book

Introduction

Calcium ions represent Mother Nature’s ‘ion-of-choice’ for regulating fundamental physiological functions, as they initiate a new life at the time of fertilization and guide subsequent developmental and physiological functions of the human body. Calcium channels, which act as gated pathways for the movement of calcium ions across the membranes, play a central part in the initiation of calcium signals, and defects in calcium channel function have been found to result in a plethora of human diseases, referred to as the calcium channelopathies.

Pathologies of Calcium Channels brings together leading international experts to discuss our current understanding of human diseases associated with the various calcium channels, from their molecular basis to potential future therapeutic targeting of calcium channels.

Keywords

Calcium signaling Channelopathies Ligand-gated channels Second messengers Voltage-gated channels

Editors and affiliations

  • Norbert Weiss
    • 1
  • Alexandra Koschak
    • 2
  1. 1.Hotchkiss Brain Institute, Department of Physiology and PharmacologyUniversity of CalgaryCalgaryCanada
  2. 2.Department of Neurophysiology and PharmacologyMedical University ViennaViennaAustria

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-642-40282-1
  • Copyright Information Springer-Verlag Berlin Heidelberg 2014
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-3-642-40281-4
  • Online ISBN 978-3-642-40282-1
  • About this book