Platelet-Rich Plasma

Regenerative Medicine: Sports Medicine, Orthopedic, and Recovery of Musculoskeletal Injuries

  • José Fábio Santos Duarte Lana
  • Maria Helena Andrade Santana
  • William Dias Belangero
  • Angela Cristina Malheiros Luzo

Part of the Lecture Notes in Bioengineering book series (LNBE)

Table of contents

  1. Front Matter
    Pages i-xvii
  2. José F. Lana, Adam Weglein, Eduardo Vicente, Amanda G. M. Perez, Ana A. Rodrigues, Ângela C. M. Luzo et al.
    Pages 1-59
  3. Amanda G. M. Perez, José F. Lana, Ana A. Rodrigues, Angela C. M. Luzo, William D. Belangero, Maria H. A. Santana
    Pages 119-138
  4. Ana A. Rodrigues, José F. Lana, Ângela C. M. Luzo, Maria H. A. Santana, Amanda G. M. Perez, D. B. Lima-Silva et al.
    Pages 139-151
  5. Adam Weglein, Steve Sampson, Danielle Aufiero
    Pages 187-201
  6. José C. Noronha
    Pages 203-213
  7. Linda Chao, Martha M. Murray, Patrick Vavken
    Pages 215-230
  8. Alberto Gobbi, Georgios Karnatzikos, Somanna Malchira, Anup Kumar
    Pages 231-236
  9. Marta Tarczyńska, Krzysztof Gaweda
    Pages 237-247
  10. David Crane, Kristin Oliver
    Pages 249-264
  11. Marko Bodor, Andrew Toy, Danielle Aufiero
    Pages 265-279
  12. André M. Cancela, José F. Lana, Joyce M. Annichino-Bizzachi, William D. Belangero, Ângela C. M. Luzo
    Pages 281-288
  13. C. H. Bittencourt, P. B. Bittencourt, O. A. L. Neto, G. C. F. Arenas
    Pages 289-313
  14. Fabricio D. Assis, Charles A. Oliveira, Thais K. Vanetti, Alexandra T. R. Luba, José F. Lana, Nelson S. A. Melo
    Pages 329-337
  15. José F. Lana, Eduardo F. Vicente, Angela B. S. D. Lana, Rodrigo K. Zogaib, Fabiano S. Magnino, Daniela B. Lima-Silva et al.
    Pages 339-360

About this book


Platelet-Rich Plasma (PRP) has gained tremendous popularity in recent years as a treatment option for specialties including Orthopedics, Dentistry, Sports Medicine, Otorhinolaryngology, Neurosurgery, Ophthalmology, Urology, Vascular, Cardiothoracic and Maxillofacial Surgery, and Veterinarian Medicine. Nowadays, PRP and Stem Cell Science have added an exciting dimension to tissue repair.

This book begins by giving the reader a broad overview of current progress as well as a discussion of the technical aspects of preparation and therapeutic use of autologous PRP. It is followed by a review of platelet structure, function and major growth factors in PRP (PDGF and TGFβ).The third chapter outlines the basic principles of biochemical cellular metabolism that increases the efficacy of PRP. Analogous to the preparation of soil for a garden, restoring cellular health should be the first consideration in Regenerative Medicine. Standardization of PRP preparation to clinical use still remains a challenging prospect. In this sense, a feasible strategy for studying PRP preparation is illustrated, which also allows to modulate and tailor the quality of PRP for further clinical applications.

The science behind PRP and stem cells, on tissue regeneration, cell proliferation and mesenchyme stem-cells are emphasized and reviewed. Various specific uses of PRP are described with detailed illustrations of various personal experiences mainly in orthopedic injuries, ligament and tend

on repair, degenerative diseases, sports medicine, chronic wound healing as well as rehabilitation aspects in tendinopathy.

Expertly written by leading scientists in the field, this book provides for beginners and experienced readers scientific fundamentals, the state of art of PRP, specific uses and personal experiences with a practical approach and reference for current trends in use. Finally, this book paves the way for future developments.


Ambulatory Therapy of Tendinopathy Ligament and Tendon Repair Osteonecrosis of the Femoral Head Plasma and Tissue Engineering Platelet-rich Plasma Recovery of Musculoskeletal Injuries Regenerative Medicine

Editors and affiliations

  • José Fábio Santos Duarte Lana
    • 1
  • Maria Helena Andrade Santana
    • 2
  • William Dias Belangero
    • 3
  • Angela Cristina Malheiros Luzo
    • 4
  1. 1.Research Institute of Sports MedicineOrthopedics and Regeneration - iMORUberabaBrazil
  2. 2.Department of Biotechnological ProcessesUniversity of CampinasCampinasBrazil
  3. 3.Department of Orthopaedic and TraumatologyUniversity of CampinasCampinasBrazil
  4. 4.Haematology and Hemotherapy CenterState University of CampinasCampinasBrazil

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 2014
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Engineering Engineering (R0)
  • Print ISBN 978-3-642-40116-9
  • Online ISBN 978-3-642-40117-6
  • Series Print ISSN 2195-271X
  • Series Online ISSN 2195-2728
  • Buy this book on publisher's site