Microstructural Parcellation of the Human Cerebral Cortex

From Brodmann's Post-Mortem Map to in Vivo Mapping with High-Field Magnetic Resonance Imaging

  • Stefan Geyer
  • Robert Turner

Table of contents

  1. Front Matter
    Pages i-viii
  2. “Classical” Cyto- and Myeloarchitectonic Human Brain Maps

  3. The Challenge of Mapping Cortical Areas Noninvasively in Living Brains

  4. “In Vivo Brodmann Mapping” with High-Field Magnetic Resonance Imaging

  5. Back Matter
    Pages 255-257

About this book

Introduction

Unraveling the functional properties of structural elements in the brain is one of the fundamental goals of neuroscientific research. In the cerebral cortex this is no mean feat, since cortical areas are defined microstructurally in post-mortem brains but functionally in living brains with electrophysiological or neuroimaging techniques – and cortical areas vary in their topographical properties across individual brains. Being able to map both microstructure and function in the same brains noninvasively in vivo would represent a huge leap forward. In recent years, high-field magnetic resonance imaging (MRI) technologies with spatial resolution below 0.5 mm have set the stage for this by detecting structural differences within the human cerebral cortex, beyond the Stria of Gennari. This provides the basis for an in vivo microanatomical brain map, with the enormous potential to make direct correlations between microstructure and function in living human brains.

This book starts with Brodmann’s post-mortem map published in the early 20th century, moves on to the almost forgotten microstructural maps of von Economo and Koskinas and the Vogt-Vogt school, sheds some light on more recent approaches that aim at mapping cortical areas noninvasively in living human brains, and culminates with the concept of “in vivo Brodmann mapping” using high-field MRI, which was introduced in the early 21st century.

Keywords

Brain maps Cortical microstructure Myeloarchitectonic pattern Neuroimaging Structure-function correlation

Editors and affiliations

  • Stefan Geyer
    • 1
  • Robert Turner
    • 2
  1. 1., Department of NeurophysicsMPI Human Cognitive and Brain SciencesLeipzigGermany
  2. 2., Department of NeurophysicsMPI Human Cognitive and Brain SciencesLeipzigGermany

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-642-37824-9
  • Copyright Information Springer-Verlag Berlin Heidelberg 2013
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-3-642-37823-2
  • Online ISBN 978-3-642-37824-9
  • About this book