Locoregional Tumor Therapy

  • Eric Van Cutsem
  • Thomas J. Vogl
  • Franco Orsi
  • Alberto Sobrero

Table of contents

  1. Front Matter
    Pages i-vi
  2. René Adam
    Pages 1-2
  3. Basics of Regional Tumor Therapies

    1. Front Matter
      Pages 3-3
    2. Martin Czejka, Katharina Schüller
      Pages 5-17
  4. Intra-arterial Therapies: Liver

    1. Front Matter
      Pages 29-29
    2. HCC
      Franco Orsi
      Pages 31-54
    3. M. Peeters
      Pages 55-72
    4. Thomas Ettrich, Thomas Seufferlein
      Pages 73-88
    5. Michel Ducreux
      Pages 89-106
  5. Intra-arterial Therapies: Lung, Head and Neck

    1. Front Matter
      Pages 107-107
    2. Thomas J. Vogl
      Pages 109-124
    3. Adorján F. Kovács
      Pages 125-138
  6. Thermoablation

    1. Front Matter
      Pages 139-139
    2. Andreas H. Mahnken, Thierry de Baère
      Pages 141-154
    3. Andreas H. Mahnken, Thierry de Baère
      Pages 155-161

About this book


Recent years have witnessed a renaissance in the use of locoregional tumor therapy as part of a multimodal therapeutic approach to a variety of solid tumors, and attempts are underway to define its value in the overall therapeutic strategy for individual tumor entities. This flourishing of interest in locoregional tumor therapy derives from a series of important new developments concerning methodology, drug treatments, and instrumentation. The resulting approaches include not only optimized locoregional chemotherapy and chemoembolization for hepatocellular carcinoma and other tumors, but also other “targeted” therapies such as stereotactic radiosurgery, radiofrequency ablation, intra-arterial administration of radiopharmaceuticals, and complex new methods of chemoembolization of liver metastases involving the use of multiagent chemotherapy in combination with targeted drugs, drug-eluting beads/microspheres, or nanoparticles. In addition, intraperitoneal and intrapleural therapies, e.g., cytoreduction plus hyperthermic intraperitoneal chemotherapy, are now a standard element of the strategy for a range of tumors. It is vital that practitioners have the necessary expertise in the use of these locoregional treatment methods and understand how to combine them optimally with modern systemic therapies. With that goal in mind, this book presents, in condensed form, the clinical results achieved using various locoregional tumor therapies. In so doing, it will allow the reader to rapidly retrieve the information on indications and effectiveness that is required for optimal integration of these highly effective therapies into modern, yet more complex treatment strategies.


HCC Intraarterial Chemotherapy Liver Metastasis TACE Thermoablation

Editors and affiliations

  • Eric Van Cutsem
    • 1
  • Thomas J. Vogl
    • 2
  • Franco Orsi
    • 3
  • Alberto Sobrero
    • 4
  1. 1.Department of OncologyUniversity Hospital Gasthuisberg Leuven Cancer InstituteLeuvenBelgium
  2. 2.Department of Diagostic RadiologyJohann Wolfgang Goethe UniversityFrankfurt am MainGermany
  3. 3.Department of RadiologyEuropean Institute of OncologyMilanoItaly
  4. 4.Department of Medical OncologyIRCCS Ospedale San Martino ISTGenovaItaly

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 2015
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Medicine Medicine (R0)
  • Print ISBN 978-3-642-36571-3
  • Online ISBN 978-3-642-36572-0
  • Buy this book on publisher's site