Myelodysplastic Syndromes

  • H. Joachim Deeg
  • David T. Bowen
  • Steven D. Gore
  • Torsten Haferlach
  • Michelle M. Le Beau
  • Charlotte Niemeyer

Part of the Hematologic Malignancies book series (HEMATOLOGIC)

Table of contents

  1. Front Matter
    Pages i-viii
  2. Epidemiology and Clinical Presentation

    1. Front Matter
      Pages 1-1
    2. Anneclaire J. De Roos
      Pages 9-38
  3. Pathology, Pathophysiology, and Staging

    1. Front Matter
      Pages 39-39
    2. Harold J. Olney, Michelle M. Le Beau
      Pages 41-72
    3. Sarah M. Greenblatt, H. Joachim Deeg, Stephen D. Nimer
      Pages 73-84
    4. Gustavo Rivero, Steven D. Gore
      Pages 97-109
    5. Manojkumar Bupathi, Ramon V. Tiu, Jaroslaw P. Maciejewski
      Pages 111-126
    6. Torsten Haferlach, Ulrike Bacher
      Pages 127-139
    7. Wolfgang Kern, Arjan A. van de Loosdrecht
      Pages 141-152
  4. Treatment

    1. Front Matter
      Pages 169-169
    2. David T. Bowen
      Pages 171-187
    3. Amer M. Zeidan, Steven D. Gore
      Pages 189-210
    4. H. Joachim Deeg
      Pages 211-228
  5. MDS in Children

    1. Front Matter
      Pages 229-229
    2. Charlotte Niemeyer
      Pages 231-240
  6. Back Matter
    Pages 241-245

About this book

Introduction

Myelodysplastic syndromes (MDS) have been studied intensively in recent years and knowledge of the disease process and underlying molecular defects in MDS has expanded rapidly.  With the aging of populations and the concurrent increase in the diagnosis of MDS, these findings are of central clinical importance. New prognostic classification systems with refined prognostic significance have been developed, and molecular abnormalities are now finding their way into the process of clinical decision-making. The book has been  completely updated since the first edition and concisely summarizes the state of the art on all aspects of MDS, including clinical presentation, etiology, epidemiology, molecular biology, classification, and staging. The different chapters provide  guidance on diagnosis and differential diagnosis, as well as on treatment strategies, including the use of hematopoietic growth factors, biology-based treatment, hematopoietic stem cell transplantation, and supportive care. MDS in children is also addressed in a separate chapter. This practically oriented book will be a valuable resource for a broad range of students and practitioners in the field.

 

Keywords

Cytognetics Hemopoietic Stem Cells Myelodysplastic Syndromes Pathophysiology

Authors and affiliations

  • H. Joachim Deeg
    • 1
  • David T. Bowen
    • 2
  • Steven D. Gore
    • 3
  • Torsten Haferlach
    • 4
  • Michelle M. Le Beau
    • 5
  • Charlotte Niemeyer
    • 6
  1. 1.Clinical Research Div.Fred Hutchinson Cancer Research CenterSeattleUSA
  2. 2., HematologyLeeds General InfirmaryLeedsUnited Kingdom
  3. 3., Department of PediatricsJohns Hopkins Oncolgoy CenterBaltimoreUSA
  4. 4.Münchner Leukämie Labor GmbH (MLL)MünchenGermany
  5. 5., Comprehensive Cancer CenterUniversity of ChicagoChicagoUSA
  6. 6.Zentrum für Kinder- und JugendmedizinUniversitätsklinikum FreiburgFreiburgGermany

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-642-36229-3
  • Copyright Information Springer-Verlag Berlin Heidelberg 2013
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Medicine
  • Print ISBN 978-3-642-36228-6
  • Online ISBN 978-3-642-36229-3
  • About this book