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New Perspectives in Regeneration

  • Ellen Heber-Katz
  • David L. Stocum

Part of the Current Topics in Microbiology and Immunology book series (CT MICROBIOLOGY, volume 367)

Table of contents

  1. Front Matter
    Pages i-x
  2. Mateusz S. Wietecha, Wendy L. Cerny, Luisa A. DiPietro
    Pages 3-32
  3. Aiko Kawasumi, Natsume Sagawa, Shinichi Hayashi, Hitoshi Yokoyama, Koji Tamura
    Pages 33-49
  4. James R. Monaghan, Malcolm Maden
    Pages 53-74
  5. Jonathan J. Henry, Alvin G. Thomas, Paul W. Hamilton, Lisa Moore, Kimberly J. Perry
    Pages 75-98
  6. Jo Ann Cameron, Derek J. Milner, Jung Seok Lee, Jianjun Cheng, Nicholas X. Fang, Iwona M. Jasiuk
    Pages 113-132
  7. Melissa M. Steward, Akshayalakshmi Sridhar, Jason S. Meyer
    Pages 163-191
  8. Günther K. H. Zupanc, Ruxandra F. Sîrbulescu
    Pages 193-233
  9. Nobuyasu Maki, Hironobu Kimura
    Pages 237-252
  10. Ellen Heber-Katz, Yong Zhang, Khamila Bedelbaeva, Fengyu Song, Xiaoping Chen, David L. Stocum
    Pages 253-276
  11. Back Matter
    Pages 277-281

About this book

Introduction

Regeneration, the homeostatic ability to maintain tissue structure in the face of normal cell turnover or loss of tissue damaged by trauma or disease, is an essential  developmental process that continues throughout life. As recently as a decade ago, any serious discussion of the possibility of regeneration becoming a practical medical tool in the near future had the air of science fiction or over-optimistic speculation. The term “regenerative medicine” was certainly on many lips but few actually expected to soon see it applied in a clinical setting. A tidal wave of discovery has changed that and investigating the cellular mechanisms of natural regeneration has become one of the hottest topics in developmental biology and biomedicine in general.

 

Many researchers entering the field find that the regeneration literature is still quite diffuse perhaps owing to the disparate biological systems that have been the object of study including hydra, planaria, newts, axolotls and more recently several mouse strains. The volume editors believe that an attempt to organize or systematize the literature is long overdue. In this volume, respected experts highlight the latest findings in vertebrate (including mammals) wound healing and regeneration. They present eleven reviews that cover a wide range of topics, from wound repair and its relationship to regeneration, through systems including lenticular, neural, and musculoskeletal tissues and limbs, to epigenetics and the role of the cell cycle. Nuclear reprogramming and cellular plasticity, which open the door for potential regenerative medical therapies for injury and degenerative disease, are recurring themes throughout the book.

We are all now part of the regeneration revolution.

Keywords

CNS regeneration DNA damage hematopoietic stem cells limb regeneration neural development wound repair

Editors and affiliations

  • Ellen Heber-Katz
    • 1
  • David L. Stocum
    • 2
  1. 1.Wistar InstitutePhiladelphiaUSA
  2. 2.Center for Regenerative Biology and, MedicineIndiana UniversityIndianapolisUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-642-35810-4
  • Copyright Information Springer-Verlag Berlin Heidelberg 2013
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-3-642-35809-8
  • Online ISBN 978-3-642-35810-4
  • Series Print ISSN 0070-217X
  • Buy this book on publisher's site