Quadruplex Nucleic Acids

  • Jonathan B. Chaires
  • David Graves

Part of the Topics in Current Chemistry book series (TOPCURRCHEM, volume 330)

Table of contents

  1. Front Matter
    Pages i-x
  2. Luigi Petraccone
    Pages 23-46
  3. Robert Hänsel, Silvie Foldynová-Trantírková, Volker Dötsch, Lukáš Trantírek
    Pages 47-65
  4. Antonio Randazzo, Gian Piero Spada, Mateus Webba da Silva
    Pages 67-86
  5. Daisuke Miyoshi, Takeshi Fujimoto, Naoki Sugimoto
    Pages 87-110
  6. Eric Largy, Anton Granzhan, Florian Hamon, Daniela Verga, Marie-Paule Teulade-Fichou
    Pages 111-177
  7. Huy T. Le, Robert Buscaglia, William L. Dean, Jonathan B. Chaires, John O. Trent
    Pages 179-210
  8. Concetta Giancola, Bruno Pagano
    Pages 211-242
  9. Phong Lan Thao Tran, Anne De Cian, Julien Gros, Rui Moriyama, Jean-Louis Mergny
    Pages 243-273
  10. Back Matter
    Pages 275-278

About this book


Gaining Insights into the Small Molecule Targeting of the G-Quadruplex in the c-MYC Promoter Using NMR and an Allele-Specific Transcriptional Assay, by Christine E. Kaiser, Vijay Gokhale, Danzhou Yang and Laurence H. Hurley.- Higher-Order Quadruplex Structures, by Luigi Petraccone.- Investigation of Quadruplex Structure Under Physiological Conditions Using In-Cell NMR, by Robert Hänsel, Silvie Foldynová-Trantírková, Volker Dötsch and Lukás Trantírek.- Circular Dichroism of Quadruplex Structures, by Antonio Randazzo, Gian Piero Spada and Mateus Webba da Silva.- Molecular Crowding and Hydration Regulating of G-Quadruplex Formation, by Daisuke Miyoshi, Takeshi Fujimoto and Naoki Sugimoto.- Visualizing the Quadruplex: From Fluorescent Ligands to Light-Up Probes, by Eric Largy, Anton Granzhan, Florian Hamon, Daniela Verga and Marie-Paule Teulade-Fichou.- Calculation of Hydrodynamic Properties for G-Quadruplex Nucleic Acid Structures from in silico Bead Models, by Huy T. Le, Robert Buscaglia, William L. Dean, Jonathan B. Chaires and John O. Trent.- Energetics of Ligand Binding to G-Quadruplexes, Concetta Giancola and Bruno Pagano.- Tetramolecular Quadruplex Stability and Assembly, by Phong Lan Thao Tran, Anne De Cian, Julien Gros, Rui Moriyama and Jean-Louis Mergny.


Circular dichroism (CD) spectroscopy DNA fluorescent probes DNA hydration G-Quadruplex complexes Higher order structure Hydrodynamic bead modelling In-Cell NMR Isothermal titration calorimetry Quadruplex-selective fluorescence probes Telomeric DNA and RNA

Editors and affiliations

  • Jonathan B. Chaires
    • 1
  • David Graves
    • 2
  1. 1.James Graham Brown Cancer CenterUniversity of LouisvilleLouisvilleUSA
  2. 2., Department of ChemistryUniversity of Alamaba at BirminghamBirminghamUSA

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 2013
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Chemistry and Materials Science
  • Print ISBN 978-3-642-34742-9
  • Online ISBN 978-3-642-34743-6
  • Series Print ISSN 0340-1022
  • Series Online ISSN 1436-5049
  • Buy this book on publisher's site