Fermentative Production, Application and Commercialization

  • Silvio Silvério da Silva
  • Anuj Kumar Chandel

Table of contents

  1. Front Matter
    Pages i-xv
  2. Biomass Hydrolysis for Xylose recovery and detoxification

    1. Front Matter
      Pages 1-1
    2. Francisco M. Gírio, Florbela Carvalheiro, Luís C. Duarte, Rafał Bogel-Łukasik
      Pages 3-37
    3. Anuj K. Chandel, Felipe A. F. Antunes, Priscila Vaz de Arruda, Thais S. S. Milessi, Silvio S. da Silva, Maria das Graças de Almeida Felipe
      Pages 39-61
    4. Tandiwe P. Mpabanga, Anuj K. Chandel, Silvio Silvério da Silva, Om V. Singh
      Pages 63-82
  3. Microorganisms, strain improvement, fermentation and biochemical methods for xylitol production

    1. Front Matter
      Pages 83-83
    2. Miho Sasaki, Masayuki Inui, Hideaki Yukawa
      Pages 109-131
    3. Rita de Cássia Lacerda Brambilla Rodrigues, Eliana Vieira Canettieri, Ernesto Acosta Martinez, Larissa Canilha, Ana Irene Napolez Solenzal, João Batista de Almeida e Silva
      Pages 133-160
    4. José Manuel Salgado, Attilio Converti, José Manuel Domínguez
      Pages 161-191
    5. Ricardo de Freitas Branco, Anuj K. Chandel, Sílvio Silvério da Silva
      Pages 193-204
    6. Attilio Converti, Patrizia Perego, José Manuel Domínguez González, Janaína Teles de Faria, Fábio Coelho Sampaio
      Pages 205-225
  4. Recovery of Xylitol and Analytical Methods for Xylitol

    1. Front Matter
      Pages 227-227
    2. Bahar Aliakbarian, Danilo de Faveri, Patrizia Perego, Attilio Converti
      Pages 229-244
    3. Zhongqi Jiang, Samuel Amartey, Zi-Hua Jiang, Wensheng Qin
      Pages 245-263
  5. Commercial Status of Xylitol Production

    1. Front Matter
      Pages 265-265
    2. Sreenivas Rao Ravella, Joe Gallagher, Steve Fish, Reddy Shetty Prakasham
      Pages 291-306
  6. Applications of Xylitol

    1. Front Matter
      Pages 307-307
    2. Annelisa Farah da Silva, Aline Siqueira Ferreira, Silvio Silvério da Silva, Nádia Rezende Barbosa Raposo
      Pages 325-342
  7. Back Matter
    Pages 343-345

About this book


Commercially, D-xylitol is produced by chemical reactions that are tailored to the requirements of various sectors. However, due to the rising interest in sustainable development and ecologically benign practices, microbial transformation processes are generally preferred over the conventional chemical conversion process. The former have multiple advantages, including less chemical load on the environment, higher efficiency, and the ability to dilute multiple downstream transformation attempts while maintaining product yield and recovery.


This book aims to disseminate the most current advances in the biotechnological production of D-xylitol and its applications in medical and health care. It is a unique collection of 15 book chapters split into 5 sections and written by experts in their respective fields, who present critical insights into several topics, review current research, and discuss future progress in this area. This book also provides essential information on hemicellulose hydrolysis to recover D-xylose, detoxification of hemicellulose hydrolysates, and improved fermentation methods for increased D-xylitol production. The highlights of strain improvement to increase the D-xylitol titers and downstream recovery of D-xylitol are also discussed in several sections. The current applications of D-xylitol in medical and health care have been used to justify the cost incurred for setting up the demonstration plant for D-xylitol production in the market. Apart from researchers and post-graduate students in the field of microbial biotechnology, this book will assist those in the business community who deal with the economic analysis of bio-based products and their marketing.


Acid Hydrolysis Detoxification Fermentation Lignocellulose Xylitol

Editors and affiliations

  • Silvio Silvério da Silva
    • 1
  • Anuj Kumar Chandel
    • 2
  1. 1., Department of BiotechnologyUniversity of São PauloSão PauloBrazil
  2. 2., Department of BiotechnologyUniversity of São PauloSão PauloBrazil

Bibliographic information