Prospects for Chemoprevention of Colorectal Neoplasia

Emerging Role of Anti-Inflammatory Drugs

  • Andrew T. Chan
  • Elmar Detering
Part of the Recent Results in Cancer Research book series (RECENTCANCER, volume 191)

Table of contents

  1. Front Matter
    Pages i-viii
  2. Dan A. Dixon, Fernando F. Blanco, Annalisa Bruno, Paola Patrignani
    Pages 7-37
  3. Melania Dovizio, Annalisa Bruno, Stefania Tacconelli, Paola Patrignani
    Pages 39-65
  4. Luis A. Garcia Rodriguez, Lucia Cea-Soriano, Stefania Tacconelli, Paola Patrignani
    Pages 67-93
  5. Sarah Kraus, Inna Naumov, Nadir Arber
    Pages 95-103
  6. Heather N. Tinsley, William E. Grizzle, Ashraf Abadi, Adam Keeton, Bing Zhu, Yaguang Xi et al.
    Pages 105-120

About this book

Introduction

The prevention of colorectal cancer is a subject of increasing medical importance, and there have been a number of promising recent developments. This book examines in detail important aspects of the current status and future prospects for chemoprevention of colorectal tumors. Research into the mechanisms that lead from early colorectal adenoma to colorectal cancer is discussed. The role and modes of action of available drugs such as celecoxib and sulindac are described, and recent data from aspirin trials are analyzed. In addition, the possible impact of nutritional agents with anti-inflammatory properties is considered, and strategies applicable in those with a high level of genetic risk are evaluated. An important feature of the book is its holistic perspective, making it relevant for gastroenterologists, internists, general practitioners, oncologists, colorectal and gastroenterological surgeons, and public health practitioners.

Keywords

Mechanisms in CRC development NSAIDs and aspirin Prevention Public health interest

Editors and affiliations

  • Andrew T. Chan
    • 1
  • Elmar Detering
    • 2
  1. 1.Massachusetts General Hospital, Gastrointestinal UnitHarvard Medical SchoolBostonUSA
  2. 2.BSP-GD-GMA-CVRM, Berlin, S101, 09, 140Bayer Schering Pharma AGBerlinGermany

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-642-30331-9
  • Copyright Information Springer-Verlag Berlin Heidelberg 2013
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Medicine
  • Print ISBN 978-3-642-30330-2
  • Online ISBN 978-3-642-30331-9
  • Series Print ISSN 0080-0015
  • About this book