Microarrays in Diagnostics and Biomarker Development

Current and Future Applications

  • Bertrand Jordan

Table of contents

  1. Front Matter
    Pages i-viii
  2. DNA Arrays

    1. Front Matter
      Pages 9-9
    2. Bertrand Jordan
      Pages 11-19
    3. Bertrand Jordan
      Pages 21-27
    4. Bertrand Jordan
      Pages 29-38
  3. Protein (Antigen and Antibody) and Peptide Arrays

    1. Front Matter
      Pages 53-53
    2. Hong Zhang, Steven Pelech, Rob Ruijtenbeek, Thomas Felgenhauer, Ralf Bischoff, Frank Breitling et al.
      Pages 81-112
    3. Jeffrey J. Walker, Edward N. Brody, Larry Gold
      Pages 113-131
  4. Other Types of Arrays

    1. Front Matter
      Pages 133-133
    2. Ronald Simon, Martina Mirlacher
      Pages 135-152
  5. Data Analysis, Commercial and Regulatory Aspects

    1. Front Matter
      Pages 169-169
    2. Benjamin Haibe-Kains, John Quackenbush
      Pages 171-210
    3. Justin Petrone
      Pages 229-236
  6. Back Matter
    Pages 237-240

About this book

Introduction

Microarray technology has made strong progress over the past decade, and there have also been significant changes in application areas, from nucleic acids to proteomics and from research to clinical applications.

This book provides a comprehensive overview of microarrays in diagnostics and biomarker development, covering DNA, peptide, protein and tissue arrays. The focus is on entities that are in actual clinical use, or quite close, and on recent developments, such as peptide and aptamer arrays. A further topic is the miniaturisation towards “nanoarrays”, which is expected to have great potential in clinical applications. Relevant issues of bioinformatics and statistical analysis of array data are discussed in detail, as well as the barriers to the commercialisation of array-based tests and the vexing IP issues involved. Thus, the book should be very useful tor active array users as well as to newcomers seeking to make the best choice between different technologies.

Keywords

Aptamer Expression Profiling Genotype Characterization Lab-on-Chip Approach Peptide Arrays Protein Arrays

Editors and affiliations

  • Bertrand Jordan
    • 1
  1. 1.CNRSLa Cadière d’AzurFrance

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-642-28203-4
  • Copyright Information Springer-Verlag Berlin Heidelberg 2012
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-3-642-28202-7
  • Online ISBN 978-3-642-28203-4
  • About this book