Appetite Control

  • Hans-Georg Joost

Part of the Handbook of Experimental Pharmacology book series (HEP, volume 209)

Table of contents

  1. Front Matter
    Pages i-x
  2. The Neuroendocrine, Hypothalamic Circuitry Regulating Hunger, Satiety, and Energy Expenditure

    1. Front Matter
      Pages 1-1
    2. Elizabeth C. Cottrell, Julian G. Mercer
      Pages 3-21
    3. Adam P. Chambers, Stephen C. Woods
      Pages 23-45
    4. Heike Biebermann, Peter Kühnen, Gunnar Kleinau, Heiko Krude
      Pages 47-75
    5. Joshua P. Nixon, Catherine M. Kotz, Colleen M. Novak, Charles J. Billington, Jennifer A. Teske
      Pages 77-109
    6. Denovan P. Begg, Stephen C. Woods
      Pages 111-129
    7. John R. W. Menzies, Karolina P. Skibicka, Emil Egecioglu, Gareth Leng, Suzanne L. Dickson
      Pages 131-158
  3. Gastrointestinal Hormones and Factors

    1. Front Matter
      Pages 159-159
    2. Henriette Kirchner, Kristy M. Heppner, Matthias H. Tschöp
      Pages 161-184
    3. Baptist Gallwitz
      Pages 185-207
    4. K. Simpson, J. Parker, J. Plumer, S. Bloom
      Pages 209-230
    5. Thomas Alexander Lutz
      Pages 231-250
    6. Michael Blaut, Susanne Klaus
      Pages 251-273
  4. Nutrient Sensing

    1. Front Matter
      Pages 275-275
    2. Bernard Thorens
      Pages 277-294
    3. M. Chevrot, C. Martin, P. Passilly-Degrace, P. Besnard
      Pages 295-307
    4. Gwen Tolhurst, Frank Reimann, Fiona M. Gribble
      Pages 309-335
  5. Agents Modifying Food Intake

  6. Back Matter
    Pages 467-474

About this book


The volume ‘Appetite Control’ provides a comprehensive description of the mechanisms controlling food intake, and thereby energy balance, in the mammalian organism.  During the last decade, research in this area has produced a remarkable wealth of information and has characterized the function of numerous peptides, transmitters, and receptors in appetite control.  Dysfunction of these circuits leads to obesity, a growing health concern.  However, the plethora of mechanistic information is in marked contrasts to an almost complete lack of anti-obesity drugs that meet the safety standards required for the chronic therapy of morbid obesity.  Consequently, ongoing research aims to identify additional targets and agents for a pharmacological intervention.  Thus, the mechanisms of appetite control as well as all agents interfering with its control are of considerable practical interest.

The authors of the volume are distinguished scientists who are leading experts in the field, and who have contributed important, original data to our understanding of the mechanisms of appetite control. They have quite different scientific backgrounds and, together, they represent all relevant disciplines. Thereby, the topics are presented from different points of view, not exclusively from that of pharmacology and neuroendocrinology. Thus, the volume addresses all scientists who are interested in the field of obesity research and the pathophysiology of appetite control.


aorexigenic agents energy homeostasis gastrointestinal hormones neuropeptides obesity

Editors and affiliations

  • Hans-Georg Joost
    • 1
  1. 1., Department of PharmacologyGerman Institute of Human NutritionNuthetalGermany

Bibliographic information