The Double [3+2] Photocycloaddition Reaction

  • Jason A. Woolford

Part of the Springer Theses book series (Springer Theses)

Table of contents

  1. Front Matter
    Pages i-xvi
  2. Jason A. Woolford
    Pages 1-26
  3. Jason A. Woolford
    Pages 27-40
  4. Jason A. Woolford
    Pages 41-47
  5. Jason A. Woolford
    Pages 113-114
  6. Jason A. Woolford
    Pages 115-176
  7. Back Matter
    Pages 177-182

About this book


Jason Woolford's thesis describes for the first time, a double [3+2] photocycloaddition of alkenes onto aromatic rings. Modern synthetic chemistry relies on the ability of researchers to uncover new and more efficient ways of creating highly complex structures. This work describes a novel, environmentally friendly photochemical step that converts in one pot, trivial starting materials into otherwise difficult to contruct fenstrane frameworks.  The rigid cores of these frameworks have significant potential in drug design. Moreover, the novelty of this work overtakes many other methods for the creation of chiral centres. No less than seven chiral centres are created in the photochemical step together with the formation of four carbon-carbon bonds  and multifused rings. Jason's innovative work has been the subject of several publications in peer-reviewed journals.


generation of molecular complexity photochemical carbon bond formation photocycloaddition reaction step economic reactions synthesis of fenestranes

Authors and affiliations

  • Jason A. Woolford
    • 1
  1. 1., Department of ChemistryUniversity of SussexFalmer BrightonUnited Kingdom

Bibliographic information