Dupuytren’s Disease and Related Hyperproliferative Disorders

Principles, Research, and Clinical Perspectives

  • Charles Eaton
  • M. Heinrich Seegenschmiedt
  • Ardeshir Bayat
  • Giulio Gabbiani
  • Paul Werker
  • Wolfgang Wach

Table of contents

  1. Front Matter
    Pages i-xxiii
  2. Anatomy, Pathology, and Pathophysiology

  3. The Myofibroblast

    1. Front Matter
      Pages 51-51
    2. Véronique Moulin, Judith Bellemare, Daniele Bergeron, Herve Genest, Michel Roy, Carlos Lopez-Vallé
      Pages 69-75
  4. Genetics and Demographics

    1. Front Matter
      Pages 85-85
    2. Guido H. C. G. Dolmans, Hans C. Hennies
      Pages 87-91
    3. Barbara Shih, Stewart Watson, Ardeshir Bayat
      Pages 93-100
    4. Latha Satish, Mark E. Baratz, Bradley Palmer, Sandra Johnson, J. Christopher Post, Garth D. Ehrlich et al.
      Pages 101-108
    5. Sandra Kraljevic Pavelic, Ivana Ratkaj
      Pages 109-113
    6. Guido H. C. G. Dolmans, Cisca Wijmenga, Roel Ophoff, Paul M. N. Werker
      Pages 115-122
    7. Dragan Zerajic, Vilhjalmur Finsen
      Pages 123-127
  5. Collagen and Cell Biology

  6. Surgical Treatment

    1. Front Matter
      Pages 185-185
    2. A. Lee Osterman, Peter M. Murray, Teresa J. Pianta
      Pages 195-205
    3. Ilse Degreef, Luc De Smet
      Pages 207-211
  7. Needle Release and Hand Therapy

    1. Front Matter
      Pages 265-265
    2. Holger C. Erne, Ahmed El Gammal, Bernhard Lukas
      Pages 293-296
    3. George A. Lawson, Anthony A. Smith
      Pages 297-303
    4. Patricia Davis, Charles Eaton
      Pages 305-316
    5. Christina Jerosch-Herold, Lee Shepstone, Adrian J. Chojnowski, Debbie Larson
      Pages 317-321
    6. Christina Jerosch-Herold, Lee Shepstone, Adrian J. Chojnowski, Debbie Larson, Elisabeth Barrett, Susan P. Vaughan
      Pages 323-332
  8. Additional and New Treatment Options

    1. Front Matter
      Pages 341-341

About this book


Until a cure exists, Dupuytren’s disease and related disorders such as Ledderhose’s disease will pose lifelong threats of functional impairment for affected individuals. A better understanding of the onset of disease, early detection and functional preservation are of the utmost importance to minimize the impact of these conditions.

This book is based on presentations and discussions at the 2010 International Symposium on Dupuytren's disease held in Miami, Florida, but it also includes new data and additional chapters. It is hoped that it will raise awareness of this underestimated condition and promote cooperative efforts to work towards a cure. Up to date information is provided on the epidemiology, biology, and pathology of the disease. The principles and specifics of treatment are explored in detail. The indications for and techniques of radiotherapy, minimally invasive treatments and open surgery are fully explained. In addition, the role of physical therapy is considered as well as the care of relapse and complications. Treatment of Ledderhose’s disease and Peyronie's disease is also discussed. This book provides invaluable information for hand surgeons, podiatrists, orthopedists, plastic surgeons, radiation therapy specialists and general practitioners. It will help to foster an interdisciplinary approach to the understanding and management of this debilitating disorder and related conditions.


Collagenase Hand surgery Medical treatment Minimally invasive surgery Morbus Dupuytren Radiotherapy

Editors and affiliations

  • Charles Eaton
    • 1
  • M. Heinrich Seegenschmiedt
    • 2
  • Ardeshir Bayat
    • 3
  • Giulio Gabbiani
    • 4
  • Paul Werker
    • 5
  • Wolfgang Wach
    • 6
  1. 1.The Hand CenterJupiterUSA
  2. 2.Strahlenzentrum HamburgHamburgGermany
  3. 3.Manchester Interdisciplinary Biocentre, Plastic & Reconstructive SurgeryUniversity of ManchesterManchesterUnited Kingdom
  4. 4.Faculty of Medicine, Dept. of Pathology and ImmunologyUniversity of GenevaGenevaSwitzerland
  5. 5.Medical Center, Department of Plastic SurgeryUniversity of GroningenGroningenNetherlands
  6. 6.Dupuytren e.V.ÜberseeGermany

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 2012
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Medicine
  • Print ISBN 978-3-642-22696-0
  • Online ISBN 978-3-642-22697-7
  • Buy this book on publisher's site