Positron Emission Tomography in Neuroscience and Clinical Neurology

  • K. Herholz
  • P. Herscovitch
  • W.-D. Heiss

Table of contents

  1. Front Matter
    Pages I-XV
  2. K. Herholz, P. Herscovitch, W.-D. Heiss
    Pages 1-5
  3. K. Herholz, P. Herscovitch, W.-D. Heiss
    Pages 7-142
  4. K. Herholz, P. Herscovitch, W.-D. Heiss
    Pages 143-185
  5. K. Herholz, P. Herscovitch, W.-D. Heiss
    Pages 187-234
  6. Back Matter
    Pages 235-297

About this book


Positron emission tomography (PET) provides unbiased in vivo measurement of local tracer activity at very high sensitivity. This is a unique property unmatched by other imaging modalities. When PETwas introduced into medicine more than 25years ago, the first organ of major interest was the brain. Since then, PET has flourished as an extremely powerful and versatile tool in scientific brain studies, whereas its use as a diagnostic tool in clinical neurology remains limited. This is in contrast to its use in otherapplications,particularlyoncology,where its value in clinical diagnosis is more widely appreciated. Wethink this situation is unfortu­ nate, because PET can contribute more to clinical neurology and clinical neuro­ science than is generally perceived today. Realization of its potential will require very close cooperation between PETexperts and clinicians and the integration of PET into clinical studies. Thus, in this book we review PETin neuroscience,with particular emphasis on findings that indicate its potential for improving diagno­ sis and treatment in neurology and psychiatry. We want to improve the trans­ ferability of the enormous scientific advances in brain PET into clinical care so as to produce tangible human benefit [1]. Wewish to guide both nuclear medicine specialists and also neurologists and psychiatrists in the use of PET. We there­ fore focus on practical and potentially clinically relevant issues, identifying solid ground as well as open questions that require further research, and we see this targeted presentation as complementary to more general PET textbooks and reviews.


Alzheimer Nuclear medicine Tumor adenosine cerebrovascular disease dementia diagnosis neurology neuroradiology neuroscience neurosurgery physiology positron emission tomography psychiatric disorder psychiatry

Authors and affiliations

  • K. Herholz
    • 1
  • P. Herscovitch
    • 2
  • W.-D. Heiss
    • 1
  1. 1.Max-Planck-Institut für Neurologische ForschungNeurologische UniversitätsklinikKölnGermany
  2. 2.PET Imaging SectionNational Institutes of Health Clinical CenterBethesdaUSA

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 2004
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-642-62283-0
  • Online ISBN 978-3-642-18766-7
  • Buy this book on publisher's site