Physical Rehabilitation of Paralysed Facial Muscles: Functional and Morphological Correlates

  • Doychin N. Angelov

Part of the Advances in Anatomy, Embryology and Cell Biology book series (ADVSANAT, volume 210)

Table of contents

  1. Front Matter
    Pages i-xii
  2. Doychin N. Angelov
    Pages 93-118
  3. Doychin N. Angelov
    Pages 119-120
  4. Back Matter
    Pages 121-143

About this book

Introduction

Using a combined morpho-functional approach the author found that polyinnervation of the neuro-muscular juction (NMJ) is the critical factor for recovery of function after transection and suture of the facial nerve. Since polyinnervation is activity-dependent and can be manipulated, the author tried to design a clinically feasible therapy by electrical stimulation or by soft tissue massage. First, electrical stimulation was applied to the transected facial nerve or to paralysed facial muscles. Both procedures did not improve vibrissal motor performance (video-based motion analysis of whisking), failed to diminish polyinnervation and even reduced the number of innervated NMJ to one fifth of normal values. In contrast, gentle stroking of the paralysed vibrissal muscles by hand resulted in full recovery of whisking. This manual stimulation depends on intact sensory supply of the denervated muscle targets and is also effective after hypoglossal-facial anastomosis, after interpositional nerve grafting, when applied to the orbicularis oculi muscle and after transection and suture of the hypoglossal nerve. From these results the author concludes that manual stimulation is a non-invasive procedure with immediate potential for clinical rehabilitation following facial nerve reconstruction.

Keywords

axonal branching axonal pathfinding intramuscular axonal sprouting muscle reinnervation peripheral nerve injury terminal Schwann cells

Authors and affiliations

  • Doychin N. Angelov
    • 1
  1. 1.Institut I für Anatomie der UniversitätKölnGermany

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-642-18120-7
  • Copyright Information Springer-Verlag Berlin Heidelberg 2011
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-3-642-18119-1
  • Online ISBN 978-3-642-18120-7
  • Series Print ISSN 0301-5556
  • Series Online ISSN 2192-7065
  • About this book