© 2011

Chemistry of Opioids

  • Hiroshi Nagase

Part of the Topics in Current Chemistry book series (TOPCURRCHEM, volume 299)

Table of contents

  1. Front Matter
    Pages i-xiii
  2. Hiroshi Nagase, Hideaki Fujii
    Pages 29-62
  3. John W. Lewis, Stephen M. Husbands
    Pages 93-119
  4. Kimberly M. Lovell, Katherine M. Prevatt-Smith, Anthony Lozama, Thomas E. Prisinzano
    Pages 141-185
  5. Hiroshi Nagase, Hideaki Fujii
    Pages 187-237
  6. Hideaki Fujii
    Pages 239-275
  7. Back Matter
    Pages 309-312

About this book


Recent Advances in the Synthesis of Morphine and Related Alkaloids; by N. Chida * Opioids in Preclinical and Clinical Trials; by H. Nagase and H. Fujii * Synthesis of 14-Alkoxymorphinan Derivatives and Their Pharmacological Actions; by H. Schmidhammer and M. Spetea * 14-Amino-4,5-Epoxymorphinan Derivatives and Their Pharmacological Actions; by J. W. Lewis and S. M. Husbands * Nonpeptidic Delta (δ) Opioid Agonists and Antagonists of the Diarylmethylpiperazine Class: What Have We Learned?; by S. N. Calderon * Synthesis of Neoclerodane Diterpenes and Their Pharmacological Effects; by K. M. Lovell, K. M. Prevatt-Smith, A. Lozama and T. E. Prisinzano * Synthesis of Novel Basic Skeletons Derived from Naltrexone; by H. Nagase and H. Fujii * Twin and Triplet Drugs in Opioid Research; by H. Fujii *  3D-Pharmacophore Identification for κ-Opioid Agonists Using Ligand-Based Drug-Design Techniques; by N. Yamaotsu and S. Hirono


14-Alkoxy compounds 14-amino compounds Morphine Synthesis Neoclerodane Diterpenes Nonpeptidic Opioid Agonists Opioid Mimetics Opioid Skeletons Triplet Drugs Twin Drugs

Editors and affiliations

  • Hiroshi Nagase
    • 1
  1. 1.School of Pharmaceutical Sciences, Dept. Medicinal ChemistryKitasato UniversityTokyoJapan

Bibliographic information