Carbon Nanotubes for Biomedical Applications

  • Rüdiger Klingeler
  • Robert B. Sim

Part of the Carbon Nanostructures book series (CARBON)

Table of contents

  1. Front Matter
    Pages i-xix
  2. Fundamentals: Synthesis of multifunctional nanomaterials and their potential for medical application

    1. Front Matter
      Pages 1-1
    2. Vittoria Raffa, Orazio Vittorio, Cristina Riggio, Gianni Ciofani, Alfred Cuschieri
      Pages 3-26
    3. Bhavna S. Paratala, Balaji Sitharaman
      Pages 27-39
    4. P. Lukanov, C.-M. Tîlmaciu, A. M. Galibert, B. Soula, E. Flahaut
      Pages 41-65
    5. E. Borowiak-Palen, C. Tripisciano, M. Rümmeli, S. Costa, X. Chen, R. J. Kalenczuk
      Pages 67-82
  3. Magnetically functionalised carbon nanotubes for medical diagnosis and therapy

    1. Front Matter
      Pages 83-83
    2. Martin Sobik, Kirsten M. Pondman, Ben Erné, Bonny Kuipers, Bennie ten Haken, Horst Rogalla
      Pages 85-95
    3. Vijay K. Anuganti, Aldrik H. Velders
      Pages 125-150
  4. Interaction with biological systems

    1. Front Matter
      Pages 151-151
    2. Constanze Lamprecht, Andreas Ebner, Ferry Kienberger, Peter Hinterdorfer
      Pages 1-16
    3. V. Neves, H. M. Coley, J. McFadden, S. R. P. Silva
      Pages 169-182
    4. Malgorzata J. Rybak-Smith, Kirsten M. Pondman, Emmanuel Flahaut, Carolina Salvador-Morales, Robert B. Sim
      Pages 183-210
  5. Towards targeted chemotherapy and gene delivery

    1. Front Matter
      Pages 221-221
    2. Elena Heister, Vera Neves, S. Ravi P. Silva, Johnjoe McFadden, Helen M. Coley
      Pages 223-245
    3. D. Haase, S. Hampel, K. Kraemer, D. Kunze, A. Taylor, M. Arlt et al.
      Pages 247-258
    4. V. Sanz-Beltrán, Ravi Silva, Helen Coley, Johnjoe McFadden
      Pages 259-273
  6. Back Matter
    Pages 275-278

About this book

Introduction

This book explores the potential of multi-functional carbon nanotubes for biomedical applications. It combines contributions from chemistry, physics, biology, engineering, and medicine. The complete overview of the state-of-the-art addresses different synthesis and biofunctionalisation routes and shows the structural and magnetic properties of nanotubes relevant to biomedical applications. Particular emphasis is put on the interaction of carbon nanotubes with biological environments, i.e. toxicity, biocompatibility, cellular uptake, intracellular distribution, interaction with the immune system and environmental impact. The insertion of NMR-active substances allows diagnostic usage as markers and sensors, e.g. for imaging and contactless local temperature sensing. The potential of nanotubes for therapeutic applications is highlighted by studies on chemotherapeutic drug filling and release, targeting and magnetic hyperthermia studies for anti-cancer treatment at the cellular level.

Keywords

NMR-active substances biocompatibility cellular uptake intracellular distribution toxicity

Editors and affiliations

  • Rüdiger Klingeler
    • 1
  • Robert B. Sim
    • 2
  1. 1.Kirchhoff Institute for PhysicsHeidelbergGermany
  2. 2.Dept. Biochemistry, Immunochemistry UnitUniversity of OxfordOxfordUnited Kingdom

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-642-14802-6
  • Copyright Information Springer -Verlag Berlin Heidelberg 2011
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Chemistry and Materials Science
  • Print ISBN 978-3-642-14801-9
  • Online ISBN 978-3-642-14802-6
  • About this book