The Chemokine System in Experimental and Clinical Hematology

  • Oystein Bruserud

Part of the Current Topics in Microbiology and Immunology book series (CT MICROBIOLOGY, volume 341)

Table of contents

  1. Front Matter
    Pages i-xi
  2. Øystein Bruserud, Astrid Olsnes Kittang
    Pages 3-12
  3. Raffaella Bonecchi, Benedetta Savino, Elena M. Borroni, Alberto Mantovani, Massimo Locati
    Pages 15-36
  4. Anna Dimberg
    Pages 59-80
  5. Juergen Loeffler, Michael Ok, Oliver C. Morton, Markus Mezger, Hermann Einsele
    Pages 83-96
  6. Astrid Olsnes Kittang, Kimberley Hatfield, Kristoffer Sand, Håkon Reikvam, Øystein Bruserud
    Pages 149-172
  7. Gary Calandra, Gary Bridger, Simon Fricker
    Pages 173-191
  8. Per Morten Sandset
    Pages 193-202
  9. Back Matter
    Pages 203-206

About this book

Introduction

The aim of the issue is to describe and explain the importance of the chemokine system in hematology. As described in the introduction the chemokine system is probably important for many aspects of normal as well as malignant hematopoiesis. A major focus is the development and treatment of hematologic malignancies, including the immunobiology of stem cell transplantation.” The present reviews illustrate that chemokines can be involved in leukemogenesis. The chemokine system is also important both for the crosstalk between malignant cells and their neighbouring nonmalignant stromal cells (including endothelial cells) as well as for immunoregulation in patients treated with allogeneic stem cell transplantation. Thus, chemokines are important both for the pathogenesis and treatment of hematological diseases.

Keywords

CXCR4 angiogenesis angiogenic chemokines angiostatic chemokine chemokine decoy receptors graft versus host disease hematopoietic cells hematopoietic stem cell transplantation heparin induced thrombocytopenia myelogenous leukemia natural killer c

Editors and affiliations

  • Oystein Bruserud
    • 1
  1. 1.Dept. Medicine, Div. Infectious DiseasesHaukeland University HospitalBergenNorway

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-642-12639-0
  • Copyright Information Springer-Verlag Berlin Heidelberg 2010
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-3-642-12638-3
  • Online ISBN 978-3-642-12639-0
  • Series Print ISSN 0070-217X
  • About this book