Table of contents

  1. Front Matter
    Pages i-xi
  2. Wen-Chi Chiang, Tim Tolker-Nielsen
    Pages 1-14
  3. Katsuji Tani, Masao Nasu
    Pages 25-37
  4. E. Y. Rykova, P. P. Laktionov, V. V. Vlassov
    Pages 93-128
  5. Patrick S. Mitchell, Muneesh Tewari
    Pages 129-145
  6. Dennis Klinman, Sven Klaschik
    Pages 191-208
  7. Shohei Koyama, Shizuo Akira, Ken J. Ishii
    Pages 209-227
  8. Back Matter
    Pages 229-232

About this book


Extracellular nucleic acids have recently emerged as important players in the fields of biology and the medical sciences. In the last several years, extracellular nucleic acids have been shown to be involved in not only microbial evolution as genetic elements but also to have structural roles in bacterial communities, such as biofilms. Circulating DNA and RNA have been found in human blood and expected to be useful as non-invasive markers for the diagnosis of several diseases. In addition, extracellular nucleic acids have attracted attention as active modulators of the immune system of higher organisms, including humans. This book covers nearly all of the newly developing fields related to extracellular nucleic acids, including those of basic biology, ecology and the medical sciences, and provides readers with the latest knowledge on them.


DNA Immune System Nucleotide RNA evolution gene expression gene transfer genes genetic engineering physiology regulation

Editors and affiliations

  • Yo Kikuchi
    • 1
  • Elena Y. Rykova
    • 2
  1. 1., Dept. of Environmental and Life SciencesToyohashi University of TechnologyToyohashi-cityJapan
  2. 2.Fundamental MedicineInstitute of Chemical Biology andNovosibirskRussian Federation

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 2010
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-3-642-12616-1
  • Online ISBN 978-3-642-12617-8
  • Series Print ISSN 0933-1891
  • Series Online ISSN 1869-2486
  • About this book