Advanced Fluorescence Reporters in Chemistry and Biology I

Fundamentals and Molecular Design

  • Alexander P. Demchenko

Part of the Springer Series on Fluorescence book series (SS FLUOR, volume 8)

Table of contents

  1. Front Matter
    Pages i-x
  2. General Aspects

  3. Design of Organic Dyes

    1. Front Matter
      Pages 25-25
    2. M. Sameiro T. Gonçalves
      Pages 27-64
    3. Leonid D. Patsenker, Anatoliy L. Tatarets, Ewald A. Terpetschnig
      Pages 65-104
    4. Olga V. Przhonska, Scott Webster, Lazaro A. Padilha, Honghua Hu, Alexey D. Kachkovski, David J. Hagan et al.
      Pages 105-147
  4. Organic Dyes with Response Function

    1. Front Matter
      Pages 187-187
    2. Mark A. Haidekker, Matthew Nipper, Adnan Mustafic, Darcy Lichlyter, Marianna Dakanali, Emmanuel A. Theodorakis
      Pages 267-308
    3. Ronald J. Clarke
      Pages 331-344
  5. Fluorophores of Visible Fluorescent Proteins

    1. Front Matter
      Pages 345-345
    2. Fabienne Merola, Bernard Levy, Isabelle Demachy, Helene Pasquier
      Pages 347-383
  6. Back Matter
    Pages 385-389

About this book


Fluorescence reporter is the key element of any sensing or imaging technology. Its optimal choice and implementation is very important for increasing the sensitivity, precision, multiplexing power, and also the spectral, temporal, and spatial reso- tion in different methods of research and practical analysis. Therefore, design of ?uorescence reporters with advanced properties is one of the most important problems. In this volume, top experts in this ?eld provide advanced knowledge on the design and properties of ?uorescent dyes. Organic dyes were the ?rst ?uorescent materials used for analytical purposes, and we observe that they retain their leading positions against strong competition of new materials – conjugated polymers, semiconductor nanocrystals, and metal chelating complexes. Recently, molecular and cellular biology got a valuable tool of organic ?uorophores synt- sized by cell machinery and incorporated into green ?uorescent protein and its analogs. Demands of various ?uorescence techniques operating in spectral, anisotropy, and time domains require focused design of ?uorescence reporters well adapted to these techniques. Near-IR spectral range becomes more and more attractive for various applications, and new dyes emitting in this range are strongly requested. Two-photonic ?uorescence has become one of the major tools in bioimaging, and ?uorescence reporters well adapted to this technique are in urgent need. These problems cannot be solved without the knowledge of fundamental principles of dye design and of physical phenomena behind their ?uorescence response.


Fluorophore UV/VIS excited states fluorescence fluorescence sensors imaging intermolecular interactions organic dyes organic photochemistry proteins

Editors and affiliations

  • Alexander P. Demchenko
    • 1
  1. 1., Palladin Institute of BiochemistryNational Academy of Sciences of UkraineKievUkraine

Bibliographic information