Radionuclide and Hybrid Bone Imaging

  • Ignac Fogelman
  • Gopinath Gnanasegaran
  • Hans van der Wall

Table of contents

  1. Front Matter
    Pages i-xiv
  2. Bone and Basics Sciences

    1. Front Matter
      Pages 1-1
    2. Rauf Yousaf
      Pages 3-27
    3. Usha Kini, B. N. Nandeesh
      Pages 29-57
    4. Hans Van der Wall, Barry Elison, Clayton Frater, Warwick Bruce, Stephen Clarke
      Pages 59-84
    5. Glen M. Blake, Michelle Frost, Amelia E. B. Moore, Muhammad Siddique, Ignac Fogelman
      Pages 85-107
    6. Geeta Hampson
      Pages 109-132
  3. Bone and Conventional Radiology

    1. Front Matter
      Pages 133-133
    2. Kathryn L. Adamson, Bruce R. Walmsley
      Pages 135-148
    3. Philippa Tyler, Sajid Butt
      Pages 149-171
    4. Sajid Hasan Butt, Thillainayagam Muthukumar, Philippa Tyler
      Pages 195-257
    5. Hans Van der Wall, Robert Loneragan, Louise Wong, Ahmed M. Mayat, John K. Pereira
      Pages 259-305
    6. Hans Van der Wall, Robert Loneragan, Louise Wong, Les Barnsley, Siri Kannangara
      Pages 307-341
  4. Radionuclide Bone Imaging: Science and Practice

    1. Front Matter
      Pages 343-343
    2. Lefteris Livieratos
      Pages 345-359
    3. Lefteris Livieratos
      Pages 361-368
    4. James R. Ballinger
      Pages 369-376
    5. Malavika Nathan, Gopinath Gnanasegaran, Kathryn Adamson, Ignac Fogelman
      Pages 377-408
    6. Fahim Ul Hassan, Malavika Nathan, Gopinath Gnanasegaran, Ignac Fogelman
      Pages 409-432

About this book


The accurate identification of pathology in the skeleton is an extremely important goal, and the great strength of the radionuclide bone scan is its ability to identify functional change before structural change occurs. Over the years, the indications for bone scan have evolved to include benign disorders as well as malignancies. Further striking developments include the emergence of PET and of new tracers that offer enhanced capabilities, such as 18F-fluoride. The most dramatic advance, however, has been the development of hybrid imaging systems that combine the strengths of different modalities.

This book, written by authors with national and international reputations in the field, covers all aspects of radionuclide and hybrid bone imaging. Introductory sections present the basic science and consider the current status and limitations of conventional radiological techniques. The underlying principles of PET-CT and SPECT-CT are carefully explained, and the value of different PET and SPECT tracers, assessed. The role of single- and dual-modality approaches in the imaging of benign bone diseases and malignancies is then discussed in detail in a series of well-illustrated chapters. The pathologies addressed include metabolic bone disease, arthritis, bone and joint infections, primary bone and soft tissue tumors, and metastases from breast and prostate cancer. A further section considers the role of bone scintigraphy in the pediatric patient, and the closing chapters focus on miscellaneous subjects, including bone densitometry and radionuclide targeted therapy.


PET tracers PET-CT SPECT tracers SPECT-CT

Editors and affiliations

  • Ignac Fogelman
    • 1
  • Gopinath Gnanasegaran
    • 2
  • Hans van der Wall
    • 3
  1. 1.School of Medicine, Dept. Nuclear MedicineGuy's, King's and St. Thomas'LondonUnited Kingdom
  2. 2.Deptartment of Nuclear MedicineGuy's and St. Thomas HospitalLondonUnited Kingdom
  3. 3.Dept. Nuclear Medicine &, Nuclear CardiologyConcord Repatriation General HospitalConcord WestAustralia

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 2012
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Medicine
  • Print ISBN 978-3-642-02399-6
  • Online ISBN 978-3-642-02400-9
  • About this book