Book
- 109 Citations
- 98 Mentions
- 15k Downloads
About this book
Introduction
Why sex matters
Among human and nonhuman animals, the prevalence and intensity of infection typically is higher in males than females and may reflect differences in exposure as well as susceptibility to pathogens. Elevated immunity among females is a double-edged sword in which it is beneficial against infectious diseases but is detrimental in terms of increased development of autoimmune diseases.
The present book critically reviews the evolutionary origin and the functional mechanisms responsible for sexual dimorphism in response to infection. It emphasizes the value of examining responses in both males and females to improve our understanding about host-pathogen interactions in both sexes.
The contributors are experts in their specific disciplines which range from microbiology and immunology to genetics, pathology, and evolutionary biology.
The book aims at bringing insight to the treatment and management of infectious diseases; it delineates areas where knowledge is lacking and highlights future avenues of research.
Keywords
autoimmune disease biology development diseases evolution evolutionary biology genetics hormone infection infectious infectious disease infectious diseases microbiology pathology treatment
Editors and affiliations
Bibliographic information
- Book Title Sex Hormones and Immunity to Infection
-
Editors
Sabra L. Klein
Craig Roberts
- DOI https://doi.org/10.1007/978-3-642-02155-8
- Copyright Information Springer-Verlag Berlin Heidelberg 2010
- Publisher Name Springer, Berlin, Heidelberg
- eBook Packages Biomedical and Life Sciences Biomedical and Life Sciences (R0)
- Hardcover ISBN 978-3-642-02154-1
- Softcover ISBN 978-3-642-42551-6
- eBook ISBN 978-3-642-02155-8
- Edition Number 1
- Number of Pages X, 319
- Number of Illustrations 0 b/w illustrations, 0 illustrations in colour
-
Topics
Immunology
Evolutionary Biology
Endocrinology
Animal Biochemistry
Animal Genetics and Genomics
Microbiology
- Buy this book on publisher's site
Reviews
From the reviews:
“This book highlights the differences between males and females in their susceptibility to infection with viruses, bacteria and parasites. … This is a well-structured and eminently readable book. Those interested in the pathogenesis of infectious disease will find this a welcome addition. Recommended for institutional purchase as students will find this a useful reference source.” (Anthony Nash, Microbiology Today, August, 2010)