From Bench to Bedside

  • Juan Iovanna
  • Uktam Ismailov

Table of contents

  1. Front Matter
    Pages i-x
  2. A. K. Saluja, V. Dudeja
    Pages 1-8
  3. J. L. Iovanna
    Pages 9-24
  4. N. Franco-Pons, E. Folch-Puy, D. Closa
    Pages 25-32
  5. G. Velasco, A. Carracedo, M. Lorente, M. Guzmán
    Pages 39-49
  6. U. S. Ismailov, N. U. Aripova, F. B. Alidjanov, M. A. Khoshimov
    Pages 75-81
  7. Back Matter
    Pages 91-92

About this book


'Pancreatology: from Bench to Bedside' focusses on recent advances in pancreatic basic research, genetics of the pancreatic diseases and its surgical management.

Basic research discusses the implication of pancreatic stress protein in acute pancreatitis and pancreatic cancer and their possible role as therapeutic targets.  Also, very original results show the unexpected role of lipids as  mediators during acute pancreatitis.  Gene screening strategies allow the detection of the genes responsbile for gemcitabine resistance of pancreatic cancer cells . They lead to the selection of several target genes, in order to suppress the resistance of cells to gemcitabine treatment. The mechanism by which tetrahydrocannabinol is anti-tumoral in pancreatic cancer cells is presented and the use of THC as a promising new therapeutic agent is discussed.

Genetic data are shown concerning hundreds of families with hereditary chronic pancreatitis and their possible role in the pathogenesis of the disease. Another very original study addresses the prevention and treatment of pancreatic diseases with diat.

In clinical  research, convincing data about the use of endoscopic sphicterotomy in the management of acute bilary pancreatitis is presented, based on the experience of a Center highly specialized in pancreatic diseases.


Basic research Clinical cancer chronic pancreatitis endoscopy genetics necrosis pancreas pancreatic cancer pathogenesis prevention screening shock surgery

Editors and affiliations

  • Juan Iovanna
    • 1
  • Uktam Ismailov
    • 2
  1. 1.Unité 624, Stress CellulaireCentre de Recherche INSERMMarseilleFrance
  2. 2.Centre of Hepatobiliary, Pancreatic SurgeryTashkent Medical AcademyTashkentUzbekistan

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 2009
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Medicine Medicine (R0)
  • Print ISBN 978-3-642-00151-2
  • Online ISBN 978-3-642-00152-9
  • Buy this book on publisher's site