Fundamentals of Tissue Engineering and Regenerative Medicine

  • Ulrich Meyer
  • Jörg Handschel
  • Hans Peter Wiesmann
  • Thomas Meyer

Table of contents

  1. Front Matter
    Pages I-XXVI
  2. General Aspects: General and Ethical Aspects

  3. Biological Considerations: Tissue and Organ Differentiation

    1. Front Matter
      Pages 57-59
    2. Mathieu Unbekandt, Jamie Davies
      Pages 61-70
    3. Thomas Meyer, Volker Ruppert, Bernhard Maisch
      Pages 71-82
  4. Engineering Strategies: Engineering at the Genetic and Molecular Level

    1. Front Matter
      Pages 89-91
    2. Wilfried Weber, Martin Fussenegger
      Pages 93-108
    3. Volker Ruppert, Sabine Pankuweit, Bernhard Maisch, Thomas Meyer
      Pages 109-120
    4. Rita A. Depprich
      Pages 121-135
  5. Engineering Strategies: Engineering at the Cellular Level

    1. Front Matter
      Pages 137-137
    2. Pensée Wu, Dafni Moschidou, Nicholas M. Fisk
      Pages 139-157
    3. Jörg Handschel, Ulrich Meyer, Hans Peter Wiesmann
      Pages 159-166
    4. Neil David Theise
      Pages 197-208
  6. Engineering Strategies: Engineering at the Tissue Level

    1. Front Matter
      Pages 209-209
    2. Ulrich Meyer, Hans Peter Wiesmann, Jörg Handschel, Norbert R. Kübler
      Pages 211-232
    3. Jeanette Libera, Klaus Ruhnau, Peter Baum, Ursus Lüthi, Thomas Schreyer, Ulrich Meyer et al.
      Pages 233-242
    4. Mark P. Lewis, Vivek Mudera, Umber Cheema, Rishma Shah
      Pages 243-253
    5. Ning Zhang, Xuejun Wen
      Pages 271-288
    6. T. Oğuz Acartürk
      Pages 289-305
    7. Jeanette Libera, Thomas Hoell, Hans-Jürgen Holzhausen, Tim Ganey, Bruno E. Gerber, Ernst M. Tetzlaff et al.
      Pages 307-315
    8. Patrick Vavken
      Pages 317-327
    9. Raymund E. Horch
      Pages 329-343
    10. James M. Mason, Paul C. Edwards
      Pages 345-367
    11. Günter Lauer
      Pages 369-380
    12. Cora Lüders, Christof Stamm, Roland Hetzer
      Pages 381-385
  7. Engineering Strategies: Engineering at the Organ Level

    1. Front Matter
      Pages 387-387
    2. Elizabeth Geddes, Xuemei Wu, Charles W. Patrick Jr.
      Pages 389-396
    3. Jung-Keug Park, Suk-Koo Lee, Doo-Hoon Lee, Young-Jin Kim
      Pages 397-410
    4. Raffaello Cortesini, Riccardo Calafiore
      Pages 411-427
    5. Alexander M. Turner, Jennifer Southgate
      Pages 429-440
    6. Christof Stamm, Cora Lüders, Boris Nasseri, Roland Hetzer
      Pages 441-452
  8. Technical Aspects: Biomaterial Related Aspects

    1. Front Matter
      Pages 453-455
    2. Hans Peter Wiesmann, Ulrich Meyer
      Pages 457-467
    3. Gavin Jell, Caterina Minelli, Molly M. Stevens
      Pages 469-484
    4. Jörg Teßmar, Ferdinand Brandl, Achim Göpferich
      Pages 495-517
  9. Technical Aspects: Scaffold Related Aspects

    1. Front Matter
      Pages 519-519
    2. Scott J. Hollister, Elly E. Liao, Erin N. Moffitt, Claire G. Jeong, Jessica M. Kemppainen
      Pages 521-537
    3. Hans Peter Wiesmann, Lydia Lammers
      Pages 539-549
    4. Jörg Handschel, Hans Peter Wiesmann, Ulrich Meyer
      Pages 551-555
  10. Technical Aspects: Laboratory Aspects and Bioreactor Use

    1. Front Matter
      Pages 557-557

About this book


Fundamentals of Tissue Engineering and Regenerative Medicine provides a complete overview of the state of the art in tissue engineering and regenerative medicine. Tissue engineering has grown tremendously during the past decade. Advances in genetic medicine and stem cell technology have significantly improved the potential to influence cell and tissue performance, and have recently expanded the field towards regenerative medicine. In recent years a number of approaches have been used routinely in daily clinical practice, others have been introduced in clinical studies, and multitudes are in the preclinical testing phase. Because of these developments, there is a need to provide comprehensive and detailed information for researchers and clinicians on this rapidly expanding field.

This book offers, in a single volume, the prerequisites of a comprehensive understanding of tissue engineering and regenerative medicine. The book is conceptualized according to a didactic approach (general aspects: social, economic, and ethical considerations; basic biological aspects of regenerative medicine: stem cell medicine, biomolecules, genetic engineering; classic methods of tissue engineering: cell, tissue, organ culture; biotechnological issues: scaffolds; bioreactors, laboratory work; and an extended medical discipline oriented approach: review of clinical use in the various medical specialties). The content of the book, written in 68 chapters by the world’s leading research and clinical specialists in their discipline, represents therefore the recent intellect, experience, and state of this bio-medical field.


Biomaterial Cell genesis Gene therapy Laboratory Regeneration Tissue genesis Transplantation bone cartilage cells genes genetic engineering surgery tissue transcription

Editors and affiliations

  • Ulrich Meyer
    • 1
  • Jörg Handschel
    • 1
  • Hans Peter Wiesmann
    • 2
  • Thomas Meyer
    • 3
  1. 1.Clinic for Maxillofacial and Plastic Facial SurgeryHeinrich Heine University DüsseldorfDüsseldorfGermany
  2. 2.Department of Experimental Maxillofacial Surgery, Biomineralisation and Tissue Engineering GroupUniversity of MünsterMünsterGermany
  3. 3.Department of Internal Medicine – CardiologyUniversity Hospital MarburgMarburgGermany

Bibliographic information

  • DOI
  • Copyright Information Springer Berlin Heidelberg 2009
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Medicine
  • Print ISBN 978-3-540-77754-0
  • Online ISBN 978-3-540-77755-7
  • Buy this book on publisher's site