Metabolomics

A Powerful Tool in Systems Biology

  • Editors
  • Jens Nielsen
  • Michael C. Jewett

Part of the Topics in Current Genetics book series (TCG, volume 18)

Table of contents

  1. Front Matter
    Pages I-XVI
  2. Jens Nielsen, Michael C. Jewett
    Pages 1-10
  3. Silas G. Villas-Bôas, Albert Koulman, Geoffrey A. Lane
    Pages 11-52
  4. Nigel Hardy, Helen Jenkins
    Pages 53-73
  5. Jan Hummel, Joachim Selbig, Dirk Walther, Joachim Kopka
    Pages 75-95
  6. Matthias Reuss, Luciano Aguilera-Vázquez, Klaus Mauch
    Pages 97-127
  7. Martin Robert, Tomoyoshi Soga, Masaru Tomita
    Pages 189-234
  8. Ulf Thrane, Birgitte Anderson, Jens C. Frisvad, Jørn Smedsgaard
    Pages 235-252
  9. Ute Roessner, Filomena Pettolino
    Pages 253-278
  10. Back Matter
    Pages 279-284

About this book

Introduction

The metabolome comprises the complete set of metabolites, the non-genetically encoded substrates, intermediates, and products of metabolic pathways, associated to a cell. Given the increasing demand to quantitatively identify the metabolome and understand how trafficking of metabolites through the metabolic network impact cellular behavior, metabolomics has emerged as an important complementary technology to the cell-wide measurements of mRNA, proteins, fluxes, and interactions (e.g. protein-DNA). Metabolomics is already a powerful tool in drug discovery and development and in metabolic engineering. While maintaining these strengths, the field promises to play a heightened role in systems biology research, which is transforming the practice of medicine and our ability to engineer living organisms.

This book brings together the latest results in the field of metabolomics. It comprehensively presents the current state of the metabolomics field by underscoring experimental methods, analysis techniques, standardization practices, and advances in specific model systems. As a result, it significantly broadens our perspective on the principles and strategies underpinning this emerging field.

Keywords

Fluxomics Functional Genomics Metabolite Analysis Metabolomics Systems Biology biology protein proteins saccharomyces cerevisiae

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-540-74719-2
  • Copyright Information Springer-Verlag Berlin Heidelberg 2007
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-3-540-74718-5
  • Online ISBN 978-3-540-74719-2
  • Series Print ISSN 1610-2096
  • Series Online ISSN 1610-6970
  • About this book