Closed-Loop Control of Blood Glucose

  • Frederick Chee
  • Tyrone Fernando

Part of the Lecture Notes in Control and Information Sciences book series (LNCIS, volume 368)

Table of contents

  1. Front Matter
    Pages I-XII
  2. Pages 1-4
  3. Pages 127-128
  4. Back Matter
    Pages 129-157

About this book


Diabetes is a disease that is now regarded an epidemic in the world and a sign- icant e?ort is directed towards ?nding better ways to manage diabetes. Keeping bloodglucoselevelsasclosetonormalaspossible,leadstoasubstantialdecrease in long term complications of diabetes and can bring signi?cant cost reductions associated with the disease. Traditionally, managing diabetes has been through intermittent monitoring of blood glucose and then administering an appropriate dose of insulin into the blood stream. This method of intermittent monitoring and administration of insulin cannot ensure blood glucose remains at near n- mal levels at all times and therefore, there is considerable interest in managing diabetes on a continuous basis. The development of arti?cial organs/apparatus that regulate human’s blood glucose level has been in progress since 1960. The aim was to measure blood glucose level ex vivo and then injecting an appropriate amount of insulin to the hyperglycaemic patient, thereby correcting the high glucose level. This aim of closing the “loop” is still being challenged by technological barriers even today, and progress are being made constantly both in overcoming the challenges and understanding more about the workings of glucose-regulatory system. The purpose of this book is to introduce the ?eld of closed-loop blood g- cose control, in a simple manner, to the reader. This includes the hardware and software components that make up the control system (see Chapter 2). The hardware components involved the di?erent types of glucose sensor (- vasive, minimally-invasive and non-invasive) and the di?erent types of insulin.


Blood Glucose Control Closed-Loop Control Algorithm Hyperglycaemia Mathematical Model Sensor algorithms physiology reading

Authors and affiliations

  • Frederick Chee
    • 1
  • Tyrone Fernando
    • 1
  1. 1.School of Electrical, Electronic and Computer EngineeringUniversity of Western AustraliaCrawleyAustralia

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 2007
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Engineering Engineering (R0)
  • Print ISBN 978-3-540-74030-8
  • Online ISBN 978-3-540-74031-5
  • Series Print ISSN 0170-8643
  • Buy this book on publisher's site