Progestins and the Mammary Gland

From Basic Science to Clinical Applications

  • Editors
  • O. Conneely
  • C. Otto

Part of the Ernst Schering Foundation Symposium Proceedings book series (SCHERING FOUND, volume 2007/1)

Table of contents

  1. Front Matter
    Pages i-xvii
  2. A. Mukherjee, P. Amato, D. Craig-Allred, F. J. DeMayo, B. W. O'Malley, J. P. Lydon
    Pages 55-76
  3. D. Medina, F. S. Kittrell, A. Tsimelzon, S. A. W. Fuqua
    Pages 109-126
  4. M. C. Pike, A. H. Wu, D. V. Spicer, S. Lee, C. L. Pearce
    Pages 127-150
  5. R. Lamb, H. Harrison, R. B. Clarke
    Pages 151-170
  6. O. M. Conneely, B. Mulac-Jericevic, R. Arnett-Mansfield
    Pages 175-185
  7. P. A. Mote, J. D. Graham, C. L. Clarke
    Pages 190-207
  8. C. Otto, B. Rohde-Schulz, G. Schwarz, I. Fuchs, M. Klewer, H. Altmann et al.
    Pages 208-235
  9. Z. Zhang, S. G. Lundeen, O. Slayden, Y. Zhu, J. Cohen, T. J. Berrodin et al.
    Pages 236-250

About these proceedings

Introduction

Progestins play a key role in reproductive endocrinology and as pharmaceutical drugs for contraception and in combined hormone therapy. To further our understanding of progestin action in the mammary gland, an international symposium, attended by leading researchers from academia and industry, was held in Berlin, 21–23 March 2007. Genetic mouse models helped to elucidate the role of progestins, both in normal breast development and in disease. Mechanistic molecular studies inspired the design of new progestins with improved tissue selectivity. In addition, the clinical impact of progesterone receptor agonists and antagonists for the prevention and treatment of breast cancer was discussed.

Keywords

Breast Cancer Endocrinology Mammary Gland Pharmacology Progesterone Receptor Regulation tissue

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-540-73493-2
  • Copyright Information Springer-Verlag Berlin Heidelberg 2008
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Medicine
  • Print ISBN 978-3-540-73492-5
  • Online ISBN 978-3-540-73493-2
  • Series Print ISSN 0947-6075
  • About this book